Risk and Immune Response to Polysaccharides. Age (i.e., elderly)Other immunocompromised groups. Protective Response Documented to Decline with Age. Production of high affinity antibodies aLong-lasting memory response to immunization bDTH to antigens seen in earlier life ca Goidl, et al. J. Exp. Med. 144, 1037 (1976)b McElhaney, et al. J. Gerentol. Med. Sci. 47, MS (1992)c Roberts-Thomson, et al., Lancet ii, 368 (1974).
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