Clotting Process . Formation of a blood clot (thrombus) in blood vessels or the heart. may be life saving (when it plugs a severed vessel) or life-threatening if it occludes a vessel supplying a vital structure. may break loose to create an embolus that flows downstream to lodge at a distant site. The potential consequence is ischemic necrosis of cells and tissues known as infarction. Cerebral vascular accidents (stroke), myocardial infarction and pulmonary embolisms are examples of diso9458
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