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Therapeutic Uses of Amanita Mascaria

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Therapeutic Uses of Amanita Mascaria

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  1. THERAPEUTIC USES OF AMANITA MUSCARIA

  2. ANXIETY / STRESS / MOOD Research on muscimol, the active compound in Amanita muscaria mushrooms, suggests potential for mood stabilization. A study by A.L. Gundlach and P.M. Beart in 1980 found that muscimol increased dopamine levels in rats. Research also finds that low levels of muscimol slightly increase serotonin. Muscimol’s sedative effects can also help calm the mind and body during a rise in stress.

  3. SEIZURES / TREMORS Muscimol, the main active ingredient in Amanita muscaria mushrooms, is currently under review for its potential to help with seizures and tremors. Quoted from clinical research from August of 2012, A muscimol concentration of 0.125 mM was well-tolerated and focally suppressed EEG activity.

  4. REDUCTION IN PAIN / INFLAMMATION Recent research published in October 2023 has found the administration of muscimol causes a significant decrease in several neuropathic pain indicators, such as mechanical allodynia, mechanical hyperalgesia, and thermal hyperalgesia. It’s also been found that muscimol protects against systemic inflammatory response in endotoxemic mice.

  5. MEMORY / BRAIN HEALTH Additionally, research indicates that Amanita muscaria mushrooms containing muscimol may positively impact memory and brain health. This is particularly relevant for treating symptoms associated with conditions such as Huntington’s Disease and Alzheimer’s. A 2018 study found muscimol exerted memory-enhancing and anti-inflammatory effects.

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