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CARM1

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CARM1

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  1. 2020/2/27 carm1 Protein, coactivator-associated arginine methyltransferase 1 - Creative BioMart (/) Product Search cat#, product name, abbr, or keywords  You Position: Home (/) /  Products (/Products-gd.htm) /  carm1 carm1 (https://www.addtoany.com/share#url=https%3A%2F%2Fwww.creativebiomart.net%2Fsymbolsearch_CARM1.htm&title=carm1%20Protein%2C%20coactiva associated%20arginine%20methyltransferase%201%20-%20Creative%20BioMart) Official Full Name coactivator-associated arginine methyltransferase 1 Background Protein arginine N-methyltransferases, such as CARM1, catalyze the transfer of a methyl group from;S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine;derivatives and S-adenosyl-L-homocysteine. Protein arginine methylation has been implicated in signal transduction,;metabolism of nascent pre-RNA, and transcriptional activation (Frankel et al., 2002 (PubMed 11724789)). Synonyms CARM1; coactivator-associated arginine methyltransferase 1; histone-arginine methyltransferase CARM1; PRMT4; protein arginine N-methyltransferase 4 Recombinant Proteins Cell & Tissue Lysates Cat.#: CARM1-0402H Tag: GST Source (Host): Wheat Germ Species: Human Product name Recombinant Human CARM1 Protein, GST-Tagged (/recombinant-human-carm1-protein-gst-tagged-488314.htm) +Inquiry (/Order.aspx?i1=(CARM1-0402H)Recombinant+Human+CARM1+Protein%2c+GST-Tagged) Cat.#: CARM1-451H Tag: N/A Source (Host): HEK293 Species: Human Product name Recombinant Human CARM1 (/description_6501_7.htm) +Inquiry (/Order.aspx?i1=(CARM1-451H)Recombinant+Human+CARM1) Cat.#: CARM1-617H Tag: His Source (Host): Sf 21 Insect cells Species: Human Product name Recombinant Human CARM1, His-tagged (/description_7115_7.htm) +Inquiry (/Order.aspx?i1=(CARM1-617H)Recombinant+Human+CARM1%2c+His-tagged) Cat.#: CARM1-176H Tag: GST Source (Host): E.coli Species: Human https://www.creativebiomart.net/symbolsearch_CARM1.htm 1/4

  2. 2020/2/27 carm1 Protein, coactivator-associated arginine methyltransferase 1 - Creative BioMart Product name Recombinant Human CARM1 Protein, GST-tagged (/recombinant-human-carm1-protein-gst-tagged-462075.htm) +Inquiry (/Order.aspx?i1=(CARM1-176H)Recombinant+Human+CARM1+Protein%2c+GST-tagged) Cat.#: CARM1-999H Tag: His|GST Source (Host): Sf 9 Insect cells Species: Human Product name Recombinant Human CARM1, Flag-tagged (/description_414485_12.htm) +Inquiry (/Order.aspx?i1=(CARM1-999H)Recombinant+Human+CARM1%2c+Flag-tagged) Cat.#: Carm1-23M Tag: FLAG Source (Host): Insect cells Species: Mouse Product name Recombinant Mouse Carm1 Protein, FLAG-tagged (/recombinant-mouse-carm1-protein-flag-tagged-481139.htm) +Inquiry (/Order.aspx?i1=(Carm1-23M)Recombinant+Mouse+Carm1+Protein%2c+FLAG-tagged) Cat.#: CARM1-2735M Tag: His Source (Host): Mammalian Cells Species: Mouse Product name Recombinant Mouse CARM1 Protein (/recombinant-mouse-carm1-protein-439716.htm) +Inquiry (/Order.aspx?i1=(CARM1-2735M)Recombinant+Mouse+CARM1+Protein) Cat.#: CARM1-1139R Tag: His Source (Host): Mammalian Cells Species: Rat Product name Recombinant Rat CARM1 Protein (/recombinant-rat-carm1-protein-449963.htm) +Inquiry (/Order.aspx?i1=(CARM1-1139R)Recombinant+Rat+CARM1+Protein) Cat.#: CARM1-1064Z Tag: His Source (Host): Mammalian Cells Species: Zebrafish Product name Recombinant Zebrafish CARM1 (/description_421354_12.htm) +Inquiry (/Order.aspx?i1=(CARM1-1064Z)Recombinant+Zebrafish+CARM1) Involved Pathway CARM1 involved in several pathways and played different roles in them. We selected most pathways CARM1 participated on our site, such as Activation of gene expression by SREBF (SREBP), Androgen receptor signaling pathway, BMAL1:CLOCK,NPAS2 activates circadian gene expression, which may be useful for your reference. Also, other proteins which involved in the same pathway with CARM1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site. Pathway Name Pathway Related Protein Activation of gene expression by SREBF (SREBP) HELZ2; CREBBP; CARM1; PMVK; CYP51A1; DHCR7; NFYAL; NFYBB; MTF1; NCOA2 Androgen receptor signaling pathway CTNNB1; KAT5; PNRC1; CREBBP; RAD9A; NCOA2; RUNX2A; ZMIZ1; RNF4; NR0B2A BMAL1:CLOCK,NPAS2 activates circadian gene expression HELZ2; NRIP1; CARM1; NCOA2; NAMPT; DBP; CRY1; CRY2; CREBBP Chromatin modifying enzymes PRMT7; ING3; SUZ12B; AEBP2; CSRP2BP; SUDS3; KAT7B; KAT7A; KANSL3; ATF7IP Chromatin organization KAT6A; SMARCC2; C20orf20; MBIP; MEAF6; SUZ12A; ELP2; KDM5D; SMARCA4; MORF4L1 https://www.creativebiomart.net/symbolsearch_CARM1.htm 2/4

  3. 2020/2/27 carm1 Protein, coactivator-associated arginine methyltransferase 1 - Creative BioMart Circadian Clock NAMPT; CRY1; RAI1; CSNK1E; HELZ2; DBP; CARM1; CPT1A; NRIP1; CRY2 Coregulation of Androgen receptor activity NRIP1; PA2G4; KDM1A; PAWR; SNURF; SVIL; CMTM2; TMF1; CTDSP1; TCF4 Developmental Biology MED25; DUSP5; NRP2; WDR83; DNM2; ARPC1B; ACTR2B; MED26; EFNA1B; NRG2A Protein Function CARM1 has several biochemical functions, for example, beta-catenin binding, histone methyltransferase activity, histone methyltransferase activity (H3- R17 specific). Some of the functions are cooperated with other proteins, some of the functions could acted by CARM1 itself. We selected most functions CARM1 had, and list some proteins which have the same functions with CARM1. You can find most of the proteins on our site. Function Related Protein Function beta-catenin binding Related Protein VCL; AXIN2; CTNNBIP1; PTPRK; SOX17; HDAC6; GLI3; APC; LEF1; TCF7L2 Function histone methyltransferase activity Related Protein PRMT6; PRDM13; CARM1; EZH2; PRMT2; PRMT1; EED; SUV39H1; SUZ12 Function histone methyltransferase activity (H3-R17 specific) Related Protein CARM1 Function histone-arginine N-methyltransferase activity Related Protein PRMT2; PRMT6; PRMT3; PRMT5; CARM1; PRMT7; PRMT8 Function ligand-dependent nuclear receptor transcription coactivator activity Related Protein MED1; SLC30A9; PPARG; ENY2; HELZ2; PUS1; ACTN1; THRAP3; DCAF6; ZCCHC18 Function lysine-acetylated histone binding Related Protein BAZ2A; BRDT; CARM1; PSME4B; BRD4; MLL1; SMARCA4; TAF1; TAF1L; BRD9 Function protein binding Related Protein THOC7; RNF175; ATG9A; RPS6KA5; SPRED2; DDX58; CCER1; RNF31; ICAM1; BCL2 Function protein homodimerization activity Related Protein BHLHA15; BCL2L10; LRRK2; DRD2; MYH9; ZNF174; HEXB; NLRC4; CDH13; CRYM Function protein methyltransferase activity Related Protein NDUFAF5; TRMT10C; RNMTL1A; METTL7B; TRMT10B; FBLL1; METTL21D; RNMTL1B; CARM1; METTL8 Function protein-arginine N-methyltransferase activity Related Protein NDUFAF5; PRDM12; PRMT2; METTL8; PRMT1; FAM86; METTL21A; METTL21D; PRMT5; PRMT8B Function protein-arginine omega-N asymmetric methyltransferase activity Related Protein PRMT8B; PRMT2; CARM1; PRMT7; PRMT8; PRMT6; PRMT1; PRMT3 Function transcription coactivator activity Related Protein TUBB3; HSF2; USP22; YY1; ENY2; GRIP1; ABT1; CALCOCO1; TADA2B; NCOA1 Function transcription regulatory region DNA binding Related Protein TOMM20A; CDK9; RREB1; JUN; TBX16; MEF2C; MTERF3; TBL1XR1; RCOR1; CEBPA Interacting Protein CARM1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull- down and so on. We selected proteins and molecules interacted with CARM1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CARM1. SMARCC1; CEBPB; CEBPB; NUDT21; DNAJA3; QKI; ORF; NRIP1; HNRNPK; UBE2I CARM1 Related Articles https://www.creativebiomart.net/symbolsearch_CARM1.htm 3/4

  4. 2020/2/27 carm1 Protein, coactivator-associated arginine methyltransferase 1 - Creative BioMart Zeng, H; Wu, JC; et al. A TR-FRET-Based Functional Assay for Screening Activators of CARM1. CHEMBIOCHEM 14:827-835(2013). Sakabe, K; Hart, GW; et al. O-GlcNAc Transferase Regulates Mitotic Chromatin Dynamics. JOURNAL OF BIOLOGICAL CHEMISTRY 285:34460-34468(2010).   45-1 Ramsey Road, Shirley, NY 11967, USA   USA: 1-631-559-9269    1-516-512-3133   Fax: 1-631-938-8127   Email: info@creative-biomart.com (mailto:info@creative-biomart.com) Enter your email here to subscribe. Your email address here submit Easy access to products and services you need from our library via powerful searching tools. Copyright © 2007 - 2020 Creative BioMart (/). All Rights Reserved. (https://twitter.com/CreaBiomart) (http://www.facebook.com/pages/Creative-Biomart/374357745946387) (http://www.linkedin.com/company/creative-biomart) (/blog/) https://www.creativebiomart.net/symbolsearch_CARM1.htm 4/4

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