1 / 6

ANGPTL4

https://www.creativebiomart.net/symbolsearch_ANGPTL4.htm<br>Angiopoietin-like protein 4 (ANGPTL4), also known as PPARu03b3 angiopoietinrelated protein, fastinginduced adipose factor, or hepatic fibrinogen /angiopoietin-related protein (HFARP), is a secreted adipokine predominantly expressed in adipose tissue and liver. The experimental results show that ANGPTL4 is a blood-borne hormone directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity. Serum levels of ANGPTL4 were decreased in patients with type 2 diabetes. In animal experiments, ANGPTL4 treatments might reduce hyperglycemia, and improve glucose tolerance by decreasing hepatic glucose production and enhancing insulin-mediated inhibition of gluconeogenesis. However, the molecular mechanisms underlying its metabolic actions remain elusive.

Allen339
Download Presentation

ANGPTL4

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. 2020/2/5 angptl4 Protein, ANGPTL4 angiopoietin-like 4 - Creative BioMart (/) Product Search cat#, product name, abbr, or keywords  You Position: Home (/) /  Products (/Products-gd.htm) /  angptl4 angptl4 (https://www.addtoany.com/share#url=https%3A%2F%2Fwww.creativebiomart.net%2Fsymbolsearch_ANGPTL4.htm&title=angptl4%20Protein%2C%20AN like%204%20-%20Creative%20BioMart) Official Full Name ANGPTL4 angiopoietin-like 4 Background Angiopoietin-like protein 4 (ANGPTL4), also known as PPARγ angiopoietinrelated protein, fastinginduced adipose factor, or hepatic fibrinogen /angiopoietin-related protein (HFARP), is a secreted adipokine predominantly expressed in adipose tissue and liver. The experimental results show that ANGPTL4 is a blood-borne hormone directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity. Serum levels of ANGPTL4 were decreased in patients with type 2 diabetes. In animal experiments, ANGPTL4 treatments might reduce hyperglycemia, and improve glucose tolerance by decreasing hepatic glucose production and enhancing insulin-mediated inhibition of gluconeogenesis. However, the molecular mechanisms underlying its metabolic actions remain elusive. Synonyms ANGPTL4; angiopoietin-like 4; angiopoietin-related protein 4; angiopoietin related protein 4; ARP4; fasting induced adipose factor; FIAF; hepatic angiopoietin related protein; hepatic fibrinogen/angiopoietin related protein; HFARP; NL2; peroxisome proliferator activated receptor (PPAR) gamma induced angiopoietin related protein; PGAR; pp1158; PPARG angiopoietin related protein; angiopoietin-like protein 4; fasting-induced adipose factor; hepatic angiopoietin-related protein; hepatic fibrinogen/angiopoietin-related protein; peroxisome proliferator-activated receptor (PPAR) gamma induced angiopoietin-related protein; ANGPTL2; Recombinant Proteins Cell & Tissue Lysates Cat.#: ANGPTL4-102H Tag: FLAG Source (Host): HEK293 Species: Human Product name Recombinant Human ANGPTL4 Protein, FLAG-tagged (/description_21058_1.htm) +Inquiry (/Order.aspx?i1=(ANGPTL4-102H)Recombinant+Human+ANGPTL4+Protein%2c+FLAG-tagged) Cat.#: ANGPTL4-159H Tag: His Source (Host): NS0 Species: Human Product name Recombinant Human ANGPTL4 Protein, His-tagged, Biotinylated (/recombinant-human-angptl4-protein-his-tagged-biotinylated-478099.htm) +Inquiry (/Order.aspx?i1=(ANGPTL4-159H)Recombinant+Human+ANGPTL4+Protein%2c+His-tagged%2c+Biotinylated) Cat.#: ANGPTL4-160H Tag: His Source (Host): NS0 Species: Human Product name Recombinant Human ANGPTL4 Protein, His-tagged, Biotinylated (/recombinant-human-angptl4-protein-his-tagged-biotinylated-478100.htm) https://www.creativebiomart.net/symbolsearch_ANGPTL4.htm 1/6

  2. 2020/2/5 angptl4 Protein, ANGPTL4 angiopoietin-like 4 - Creative BioMart +Inquiry (/Order.aspx?i1=(ANGPTL4-160H)Recombinant+Human+ANGPTL4+Protein%2c+His-tagged%2c+Biotinylated) Cat.#: ANGPTL4-231H Tag: Fc Source (Host): HEK293 Species: Human Product name Recombinant Human ANGPTL4 Protein, Fc-tagged (/recombinant-human-angptl4-protein-fc-tagged-464036.htm) +Inquiry (/Order.aspx?i1=(ANGPTL4-231H)Recombinant+Human+ANGPTL4+Protein%2c+Fc-tagged) Cat.#: ANGPTL4-268H Tag: His Source (Host): CHO Species: Human Product name Recombinant Human ANGPTL4 protein, His-tagged (/recombinant-human-angptl4-protein-his-tagged-469289.htm) +Inquiry (/Order.aspx?i1=(ANGPTL4-268H)Recombinant+Human+ANGPTL4+protein%2c+His-tagged) Cat.#: ANGPTL4-26H Tag: His Source (Host): NS0 Species: Human Product name Recombinant Human ANGPTL4, His-tagged (/description_413142_12.htm) +Inquiry (/Order.aspx?i1=(ANGPTL4-26H)Recombinant+Human+ANGPTL4%2c+His-tagged) Cat.#: ANGPTL4-27H Tag: GST Source (Host): Wheat germ Species: Human Product name Recombinant Human ANGPTL4, GST-tagged (/description_413144_12.htm) +Inquiry (/Order.aspx?i1=(ANGPTL4-27H)Recombinant+Human+ANGPTL4%2c+GST-tagged) Cat.#: ANGPTL4-430H Tag: Fc Source (Host): HEK293 Species: Human Product name Recombinant Human ANGPTL4, His tagged (/description_387939_12.htm) +Inquiry (/Order.aspx?i1=(ANGPTL4-430H)Recombinant+Human+ANGPTL4%2c+His+tagged) Cat.#: ANGPTL4-495H Tag: His|DDK Source (Host): HEK293 cells Species: Human Product name Recombinant Human ANGPTL4 Protein, His/DDK-tagged (/recombinant-human-angptl4-protein-hisddk-tagged-479882.htm) +Inquiry (/Order.aspx?i1=(ANGPTL4-495H)Recombinant+Human+ANGPTL4+Protein%2c+His%2fDDK-tagged) Cat.#: ANGPTL4-496H Tag: DDK|His Source (Host): HEK293 cells Species: Human Product name Recombinant Human ANGPTL4 Protein, DDK/His-tagged (/recombinant-human-angptl4-protein-ddkhis-tagged-479883.htm) +Inquiry (/Order.aspx?i1=(ANGPTL4-496H)Recombinant+Human+ANGPTL4+Protein%2c+DDK%2fHis-tagged) Cat.#: ANGPTL4-557H Tag: GST Source (Host): Wheat Germ Species: Human https://www.creativebiomart.net/symbolsearch_ANGPTL4.htm 2/6

  3. 2020/2/5 angptl4 Protein, ANGPTL4 angiopoietin-like 4 - Creative BioMart Product name Recombinant Human ANGPTL4 protein, GST-tagged (/recombinant-human-angptl4-protein-gst-tagged-480218.htm) +Inquiry (/Order.aspx?i1=(ANGPTL4-557H)Recombinant+Human+ANGPTL4+protein%2c+GST-tagged) Cat.#: ANGPTL4-5742H Tag: His|GST Source (Host): E. coli Species: Human Product name Recombinant Human ANGPTL4 protein, His & GST-tagged (/recombinant-human-angptl4-protein-his-gst-tagged-481925.htm) +Inquiry (/Order.aspx?i1=(ANGPTL4-5742H)Recombinant+Human+ANGPTL4+protein%2c+His+%26+GST-tagged) Cat.#: ANGPTL4-98H Tag: Flag Source (Host): HEK293 Species: Human Product name Recombinant Human ANGPTL4, FLAG-tagged (/description_390333_12.htm) +Inquiry (/Order.aspx?i1=(ANGPTL4-98H)Recombinant+Human+ANGPTL4%2c+FLAG-tagged) Cat.#: Angptl4-101M Tag: Flag Source (Host): HEK293 Species: Mouse Product name Recombinant Mouse Angptl4, FLAG-tagged (/description_390334_12.htm) +Inquiry (/Order.aspx?i1=(Angptl4-101M)Recombinant+Mouse+Angptl4%2c+FLAG-tagged) Cat.#: Angptl4-105M Tag: Flag Source (Host): COS-7 Species: Mouse Product name Recombinant Mouse Angptl4, FLAG-tagged (/description_390337_12.htm) +Inquiry (/Order.aspx?i1=(Angptl4-105M)Recombinant+Mouse+Angptl4%2c+FLAG-tagged) Cat.#: Angptl4-476M Tag: His Source (Host): HEK293 Species: Mouse Product name Recombinant Mouse Angptl4, His-tagged (/description_396003_12.htm) +Inquiry (/Order.aspx?i1=(Angptl4-476M)Recombinant+Mouse+Angptl4%2c+His-tagged) Cat.#: Angptl4-5743M Tag: His Source (Host): E. coli Species: Mouse Product name Recombinant Mouse Angptl4 protein, His-tagged (/recombinant-mouse-angptl4-protein-his-tagged-481926.htm) +Inquiry (/Order.aspx?i1=(Angptl4-5743M)Recombinant+Mouse+Angptl4+protein%2c+His-tagged) Cat.#: Angptl4-102R Tag: Flag Source (Host): HEK293 Species: Rat Product name Recombinant Rat Angptl4, FLAG-tagged (/description_390335_12.htm) +Inquiry (/Order.aspx?i1=(Angptl4-102R)Recombinant+Rat+Angptl4%2c+FLAG-tagged) Cat.#: Angptl4-104R Tag: His https://www.creativebiomart.net/symbolsearch_ANGPTL4.htm 3/6

  4. 2020/2/5 angptl4 Protein, ANGPTL4 angiopoietin-like 4 - Creative BioMart Source (Host): E. coli Species: Rat Product name Recombinant Rat Angptl4, His-tagged (/description_390336_12.htm) +Inquiry (/Order.aspx?i1=(Angptl4-104R)Recombinant+Rat+Angptl4%2c+His-tagged) Cat.#: Angptl4-5745R Tag: His|T7 Source (Host): E. coli Species: Rat Product name Recombinant Rat Angptl4 protein, His & T7-tagged (/recombinant-rat-angptl4-protein-his-t7-tagged-481928.htm) +Inquiry (/Order.aspx?i1=(Angptl4-5745R)Recombinant+Rat+Angptl4+protein%2c+His+%26+T7-tagged) Cat.#: ANGPTL4-670R Tag: His Source (Host): Mammalian Cells Species: Rat Product name Recombinant Rat ANGPTL4 Protein (/recombinant-rat-angptl4-protein-449494.htm) +Inquiry (/Order.aspx?i1=(ANGPTL4-670R)Recombinant+Rat+ANGPTL4+Protein) Cat.#: ANGPTL4-8125Z Tag: His Source (Host): Mammalian Cells Species: Zebrafish Product name Recombinant Zebrafish ANGPTL4 (/description_428333_12.htm) +Inquiry (/Order.aspx?i1=(ANGPTL4-8125Z)Recombinant+Zebrafish+ANGPTL4) Cat.#: ANGPTL4-5741C Tag: His Source (Host): E. coli Species: Cattle Product name Recombinant Cattle ANGPTL4 protein, His-tagged (/recombinant-cattle-angptl4-protein-his-tagged-481924.htm) +Inquiry (/Order.aspx?i1=(ANGPTL4-5741C)Recombinant+Cattle+ANGPTL4+protein%2c+His-tagged) Cat.#: ANGPTL4-5744P Tag: His Source (Host): E. coli Species: Pig Product name Recombinant Pig ANGPTL4 protein, His-tagged (/recombinant-pig-angptl4-protein-his-tagged-481927.htm) +Inquiry (/Order.aspx?i1=(ANGPTL4-5744P)Recombinant+Pig+ANGPTL4+protein%2c+His-tagged) Cat.#: ANGPTL4-118H Tag: His Source (Host): E. coli Species: Human Product name Recombinant Human Angiopoietin-like 4, His-tagged (/description_3876_16.htm) +Inquiry (/Order.aspx?i1=(ANGPTL4-118H)Recombinant+Human+Angiopoietin-like+4%2c+His-tagged) Cat.#: ANGPTL4-403H Tag: Flag Source (Host): HEK293 Species: Human Product name Recombinant Human ANGPTL4, Fibrinogen-like Domain, FLAG-tagged (/description_7026_16.htm) +Inquiry (/Order.aspx?i1=(ANGPTL4-403H)Recombinant+Human+ANGPTL4%2c+Fibrinogen-like+Domain%2c+FLAG-tagged) https://www.creativebiomart.net/symbolsearch_ANGPTL4.htm 4/6

  5. 2020/2/5 angptl4 Protein, ANGPTL4 angiopoietin-like 4 - Creative BioMart Cat.#: ANGPTL4-404H Tag: His Source (Host): CHO Species: Human Product name Recombinant Human Angiopoietin-like 4, His-tagged (/description_7027_16.htm) +Inquiry (/Order.aspx?i1=(ANGPTL4-404H)Recombinant+Human+Angiopoietin-like+4%2c+His-tagged) Cat.#: ANGPTL4-497H Tag: His Source (Host): E. coli Species: Human Product name Recombinant Human ANGPTL4, His-tagged (/description_21253_16.htm) +Inquiry (/Order.aspx?i1=(ANGPTL4-497H)Recombinant+Human+ANGPTL4%2c+His-tagged) Cat.#: ANGPTL4-402M Tag: His Source (Host): HEK293 Species: Mouse Product name Recombinant Mouse Angiopoietin-like 4, Coiled-Coil Domain, His-tagged (/description_7079_16.htm) +Inquiry (/Order.aspx?i1=(ANGPTL4-402M)Recombinant+Mouse+Angiopoietin-like+4%2c+Coiled-Coil+Domain%2c+His-tagged) Cat.#: Angptl4-405M Tag: Flag Source (Host): COS-7 Species: Mouse Product name Recombinant Mouse Angiopoietin-like 4, FLAG-tagged (/description_7028_16.htm) +Inquiry (/Order.aspx?i1=(Angptl4-405M)Recombinant+Mouse+Angiopoietin-like+4%2c+FLAG-tagged) Cat.#: Angptl4-406M Tag: N/A Source (Host): Species: Mouse Product name Recombinant Mouse Angptl4, His-tagged (/description_383045_16.htm) +Inquiry (/Order.aspx?i1=(Angptl4-406M)Recombinant+Mouse+Angptl4%2c+His-tagged) Involved Pathway ANGPTL4 involved in several pathways and played different roles in them. We selected most pathways ANGPTL4 participated on our site, such as PPAR signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ANGPTL4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site. Pathway Name Pathway Related Protein PPAR signaling pathway PPARAB; Scd1; ACSL3; SCD5; SCD; RXRBA; PPARDB; APOC3; ACSL4A; RXRA Protein Function ANGPTL4 has several biochemical functions, for example, enzyme inhibitor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ANGPTL4 itself. We selected most functions ANGPTL4 had, and list some proteins which have the same functions with ANGPTL4. You can find most of the proteins on our site. Function Related Protein Function enzyme inhibitor activity https://www.creativebiomart.net/symbolsearch_ANGPTL4.htm 5/6

  6. 2020/2/5 angptl4 Protein, ANGPTL4 angiopoietin-like 4 - Creative BioMart Related Protein OAZ2B; NOTCH1; SCG5; CSN2; ARRB1; SLN; PDE6G; UGT1A9; TAE1; APBA3 Function protein binding Related Protein OAS1A; PI4KA; UBE2E1; RNF144B; NLRX1; ABCF1; DHX8; TTC17; ARSI; APOA4 Interacting Protein ANGPTL4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull- down and so on. We selected proteins and molecules interacted with ANGPTL4 here. Most of them are supplied by our site. Hope this information will be useful for your research of ANGPTL4. ITGB5; ITGB1; AURKA; TGFB1; ESR1; FGFR4; CDKN2A; CDKN2C; CASP8; FBXW7; BRMS1; RAC1; PTK2   45-1 Ramsey Road, Shirley, NY 11967, USA   USA: 1-631-559-9269    1-516-512-3133   Europe: 44-207-097-1828   Fax: 1-631-938-8127   Email: info@creative-biomart.com (mailto:info@creative-biomart.com) Enter your email here to subscribe. Your email address here submit Easy access to products and services you need from our library via powerful searching tools. Copyright © 2007 - 2020 Creative BioMart (/). All Rights Reserved. (https://twitter.com/CreaBiomart) (http://www.facebook.com/pages/Creative-Biomart/374357745946387) (http://www.linkedin.com/company/creative-biomart) (/blog/) https://www.creativebiomart.net/symbolsearch_ANGPTL4.htm 6/6

More Related