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ANGPT1

https://www.creativebiomart.net/symbolsearch_ANGPT1.htm<br>Angiopoietin-1 is a 498 amino acid secreted protein that undergoes post-translational glycosylation. It contains 1 fibrinogen C-terminal domain. Angiopoietin-1 is found to bind and activate TIE2 receptors by inducing its tyrosine phosphorylation. It is implicated in endothelial developmental processes later and is distinct from that of VEGF. Angiopoietin-1 appears to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. Moreover, it mediates blood vessel maturation/stability. Angiopoietin-1 may also play an important role in early development of the heart. It may have a potential therapeutic utility since it can be used for specifically targeting tumor vasculature or for promoting angiogenic processes in certain organs such as an ischemic heart.

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ANGPT1

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  1. 2020/2/5 angpt1 Protein, Angiopoietin 1 - Creative BioMart (/) Product Search cat#, product name, abbr, or keywords  You Position: Home (/) /  Products (/Products-gd.htm) /  angpt1 angpt1 (https://www.addtoany.com/share#url=https%3A%2F%2Fwww.creativebiomart.net%2Fsymbolsearch_ANGPT1.htm&title=angpt1%20Protein%2C%20Angio %20Creative%20BioMart) Official Full Name Angiopoietin 1 Background Angiopoietin-1 is a 498 amino acid secreted protein that undergoes post-translational glycosylation. It contains 1 fibrinogen C-terminal domain. Angiopoietin-1 is found to bind and activate TIE2 receptors by inducing its tyrosine phosphorylation. It is implicated in endothelial developmental processes later and is distinct from that of VEGF. Angiopoietin-1 appears to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. Moreover, it mediates blood vessel maturation/stability. Angiopoietin-1 may also play an important role in early development of the heart. It may have a potential therapeutic utility since it can be used for specifically targeting tumor vasculature or for promoting angiogenic processes in certain organs such as an ischemic heart. Synonyms ANGPT1; AGP1; AGPT; ANG1; ANG-1 Recombinant Proteins Cell & Tissue Lysates Cat.#: ANGPT1-159H Tag: HIgG1 Fc Source (Host): HEK293 Species: Human Product name Recombinant Human ANGPT1 Protein, HIgG1 Fc-tagged (/recombinant-human-angpt1-protein-higg1-fc-tagged-504420.htm) +Inquiry (/Order.aspx?i1=(ANGPT1-159H)Recombinant+Human+ANGPT1+Protein%2c+HIgG1+Fc-tagged) Cat.#: Angpt1-539R Tag: His Source (Host): Yeast Species: Rat Product name Recombinant Rat Angpt1 protein, His-tagged (/recombinant-rat-angpt1-protein-his-tagged-507406.htm) +Inquiry (/Order.aspx?i1=(Angpt1-539R)Recombinant+Rat+Angpt1+protein%2c+His-tagged) Cat.#: ANGPT1-1065H Tag: HlgG1 Fc Source (Host): HEK293 Species: Human Product name Recombinant Human ANGPT1 Protein (Met1-Leu261 and Arg277-Phe498), HlgG1 Fc-tagged (/recombinant-human-angpt1-protein-met1-leu261-and- arg277-phe498-hlgg1-fc-tagged-504730.htm) +Inquiry (/Order.aspx?i1=(ANGPT1-1065H)Recombinant+Human+ANGPT1+Protein+(Met1-Leu261+and+Arg277-Phe498)%2c+HlgG1+Fc-tagged) https://www.creativebiomart.net/symbolsearch_ANGPT1.htm 1/6

  2. 2020/2/5 angpt1 Protein, Angiopoietin 1 - Creative BioMart Cat.#: ANGPT1-1066C Tag: HlgG1 Fc Source (Host): HEK293 Species: Cynomolgus Product name Recombinant Cynomolgus ANGPT1 Protein (Arg277-Phe498), HlgG1 Fc-tagged (/recombinant-cynomolgus-angpt1-protein-arg277-phe498-hlgg1- fc-tagged-504731.htm) +Inquiry (/Order.aspx?i1=(ANGPT1-1066C)Recombinant+Cynomolgus+ANGPT1+Protein+(Arg277-Phe498)%2c+HlgG1+Fc-tagged) Cat.#: ANGPT1-115H Tag: MYC Source (Host): Baculovirus-Insect Cells Species: Human Product name Recombinant Human Angiopoietin 1, Myc-tagged (/description_3873_7.htm) +Inquiry (/Order.aspx?i1=(ANGPT1-115H)Recombinant+Human+Angiopoietin+1%2c+Myc-tagged) Cat.#: ANGPT1-2518H Tag: N/A Source (Host): NS0 Species: Human Product name Recombinant Human Angiopoietin 1 (/description_9795_7.htm) +Inquiry (/Order.aspx?i1=(ANGPT1-2518H)Recombinant+Human+Angiopoietin+1) Cat.#: ANGPT1-27316TH Tag: N/A Source (Host): E. coli Species: Human Product name Recombinant Human ANGPT1 (/description_61568_7.htm) +Inquiry (/Order.aspx?i1=(ANGPT1-27316TH)Recombinant+Human+ANGPT1) Cat.#: ANGPT1-27317TH Tag: Flag Source (Host): E. coli Species: Human Product name Recombinant Human ANGPT1, FLAG-tagged (/description_61569_7.htm) +Inquiry (/Order.aspx?i1=(ANGPT1-27317TH)Recombinant+Human+ANGPT1%2c+FLAG-tagged) Cat.#: ANGPT1-434H Tag: Flag Source (Host): CHO Species: Human Product name Recombinant Human Angiopoietin 1, FLAG-tagged (/description_899_7.htm) +Inquiry (/Order.aspx?i1=(ANGPT1-434H)Recombinant+Human+Angiopoietin+1%2c+FLAG-tagged) Cat.#: COMP-Ang1-01 Tag: N/A Source (Host): CHO Species: Rat and Human Product name Recombinant Comp(Rat) and ANGPT1(Human), Flag-tagged (/description_383023_7.htm) +Inquiry (/Order.aspx?i1=(COMP-Ang1-01)Recombinant+Comp(Rat)+and+ANGPT1(Human)%2c+Flag-tagged) Cat.#: Ang-1-3455H Tag: N/A Source (Host): HeLa cells Species: Human Product name Recombinant Human Ang-1 (/description_396594_12.htm) https://www.creativebiomart.net/symbolsearch_ANGPT1.htm 2/6

  3. 2020/2/5 angpt1 Protein, Angiopoietin 1 - Creative BioMart +Inquiry (/Order.aspx?i1=(Ang-1-3455H)Recombinant+Human+Ang-1) Cat.#: ANGPT1-157H Tag: His Source (Host): NS0 Species: Human Product name Recombinant Human ANGPT1 Protein, His-tagged, Biotinylated (/recombinant-human-angpt1-protein-his-tagged-biotinylated-478097.htm) +Inquiry (/Order.aspx?i1=(ANGPT1-157H)Recombinant+Human+ANGPT1+Protein%2c+His-tagged%2c+Biotinylated) Cat.#: ANGPT1-256H Tag: GST Source (Host): Wheat Germ Species: Human Product name Recombinant Human ANGPT1 protein, GST-tagged (/recombinant-human-angpt1-protein-gst-tagged-465930.htm) +Inquiry (/Order.aspx?i1=(ANGPT1-256H)Recombinant+Human+ANGPT1+protein%2c+GST-tagged) Cat.#: ANGPT1-3455H Tag: His Source (Host): HELA Species: Human Product name Recombinant Human ANGPT1 protein, His-tagged (/recombinant-human-angpt1-protein-his-tagged-467037.htm) +Inquiry (/Order.aspx?i1=(ANGPT1-3455H)Recombinant+Human+ANGPT1+protein%2c+His-tagged) Cat.#: ANGPT1-35H Tag: FLAG Source (Host): HEK293 Species: Human Product name Recombinant Human ANGPT1/COMP protein, FLAG-tagged (/recombinant-human-angpt1comp-protein-flag-tagged-465921.htm) +Inquiry (/Order.aspx?i1=(ANGPT1-35H)Recombinant+Human+ANGPT1%2fCOMP+protein%2c+FLAG-tagged) Cat.#: ANGPT1-525H Tag: His Source (Host): E. coli Species: Human Product name Recombinant Human ANGPT1 protein, His-tagged (/recombinant-human-angpt1-protein-his-tagged-470914.htm) +Inquiry (/Order.aspx?i1=(ANGPT1-525H)Recombinant+Human+ANGPT1+protein%2c+His-tagged) Cat.#: ANGPT1-526H Tag: His Source (Host): E. coli Species: Human Product name Recombinant Human ANGPT1 protein, His-tagged (/recombinant-human-angpt1-protein-his-tagged-470915.htm) +Inquiry (/Order.aspx?i1=(ANGPT1-526H)Recombinant+Human+ANGPT1+protein%2c+His-tagged) Cat.#: ANGPT1-6881H Tag: N/A Source (Host): E. coli Species: Human Product name Recombinant Human Angiopoietin 1 (/description_108436_12.htm) +Inquiry (/Order.aspx?i1=(ANGPT1-6881H)Recombinant+Human+Angiopoietin+1) Cat.#: Angpt1-4964M Tag: N/A Source (Host): COS Species: Mouse https://www.creativebiomart.net/symbolsearch_ANGPT1.htm 3/6

  4. 2020/2/5 angpt1 Protein, Angiopoietin 1 - Creative BioMart Product name Recombinant Mouse Angpt1 protein (/description_106209_12.htm) +Inquiry (/Order.aspx?i1=(Angpt1-4964M)Recombinant+Mouse+Angpt1+protein) Cat.#: Angpt1-527M Tag: His Source (Host): E. coli Species: Mouse Product name Recombinant Mouse Angpt1 protein, His-tagged (/recombinant-mouse-angpt1-protein-his-tagged-470916.htm) +Inquiry (/Order.aspx?i1=(Angpt1-527M)Recombinant+Mouse+Angpt1+protein%2c+His-tagged) Cat.#: Angpt1-528M Tag: His Source (Host): E. coli Species: Mouse Product name Recombinant Mouse Angpt1 protein, His-tagged (/recombinant-mouse-angpt1-protein-his-tagged-470917.htm) +Inquiry (/Order.aspx?i1=(Angpt1-528M)Recombinant+Mouse+Angpt1+protein%2c+His-tagged) Cat.#: Angpt1-857M Tag: His Source (Host): HEK293 Species: Mouse Product name Recombinant Mouse Angpt1 Protein, His-tagged (/recombinant-mouse-angpt1-protein-his-tagged-465162.htm) +Inquiry (/Order.aspx?i1=(Angpt1-857M)Recombinant+Mouse+Angpt1+Protein%2c+His-tagged) Cat.#: Angpt1-529R Tag: His Source (Host): E. coli Species: Rat Product name Recombinant Rat Angpt1 protein, His-tagged (/recombinant-rat-angpt1-protein-his-tagged-470918.htm) +Inquiry (/Order.aspx?i1=(Angpt1-529R)Recombinant+Rat+Angpt1+protein%2c+His-tagged) Cat.#: ANGPT1-668R Tag: His Source (Host): Mammalian Cells Species: Rat Product name Recombinant Rat ANGPT1 Protein (/recombinant-rat-angpt1-protein-449492.htm) +Inquiry (/Order.aspx?i1=(ANGPT1-668R)Recombinant+Rat+ANGPT1+Protein) Cat.#: ANGPT1-1171C Tag: His Source (Host): HEK293 Species: Cynomolgus Monkey Product name Recombinant Cynomolgus ANGPT1 Protein, His-tagged (/recombinant-cynomolgus-angpt1-protein-his-tagged-465474.htm) +Inquiry (/Order.aspx?i1=(ANGPT1-1171C)Recombinant+Cynomolgus+ANGPT1+Protein%2c+His-tagged) Cat.#: ANGPT1-324R Tag: His Source (Host): Mammalian Cells Species: Rhesus Macaque Product name Recombinant Rhesus monkey ANGPT1 Protein, His-tagged (/recombinant-rhesus-monkey-angpt1-protein-his-tagged-456973.htm) +Inquiry (/Order.aspx?i1=(ANGPT1-324R)Recombinant+Rhesus+monkey+ANGPT1+Protein%2c+His-tagged) Cat.#: ANGPT1-523D Tag: His https://www.creativebiomart.net/symbolsearch_ANGPT1.htm 4/6

  5. 2020/2/5 angpt1 Protein, Angiopoietin 1 - Creative BioMart Source (Host): E. coli Species: Dog Product name Recombinant Dog ANGPT1 protein, His-tagged (/recombinant-dog-angpt1-protein-his-tagged-470912.htm) +Inquiry (/Order.aspx?i1=(ANGPT1-523D)Recombinant+Dog+ANGPT1+protein%2c+His-tagged) Cat.#: ANGPT1-524D Tag: His Source (Host): E. coli Species: Dog Product name Recombinant Dog ANGPT1 protein, His-tagged (/recombinant-dog-angpt1-protein-his-tagged-470913.htm) +Inquiry (/Order.aspx?i1=(ANGPT1-524D)Recombinant+Dog+ANGPT1+protein%2c+His-tagged) Cat.#: ANGPT1-4313C Tag: His Source (Host): Mammalian Cells Species: Chicken Product name Recombinant Chicken ANGPT1 (/description_417619_12.htm) +Inquiry (/Order.aspx?i1=(ANGPT1-4313C)Recombinant+Chicken+ANGPT1) Cat.#: ANGPT1-9324Z Tag: His Source (Host): Mammalian Cells Species: Zebrafish Product name Recombinant Zebrafish ANGPT1 (/description_429497_12.htm) +Inquiry (/Order.aspx?i1=(ANGPT1-9324Z)Recombinant+Zebrafish+ANGPT1) Involved Pathway ANGPT1 involved in several pathways and played different roles in them. We selected most pathways ANGPT1 participated on our site, such as Ras signaling pathway, Rap signaling pathway, HIF- signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ANGPT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site. Pathway Name Pathway Related Protein Ras signaling pathway ANGPT2; PRKCA; MAP2K2; MAPK1; MRAS; PLCG2; PLA2G12A; GRIN2B; FLT4; MAPK10 Rap signaling pathway APBB1IP; KRAS; THBS1; PIK3R2; MAGI2; FGF5; KITLG; PRKCB; FGF3; FGF8 HIF- signaling pathway EIF4E2; PLCG1; ERBB2; IFNG; CAMK2A; IFNGR2; ALDOA; RPS6KB2; MAPK1; TCEB2 PIK-Akt signaling pathway GNG10; TNC; IFNB1; IRS1; TLR4; GNG4; FGF21; GNGT2; GH2; ITGA2 Rheumatoid arthritis CCL20; LTB; TLR4; ICAM1; ATP6V1B1; FLT1; HLA-DRB5; ATP6V0B; Ctsl; ATP6V1B2 Protein Function ANGPT1 has several biochemical functions, for example, protein binding, receptor tyrosine kinase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ANGPT1 itself. We selected most functions ANGPT1 had, and list some proteins which have the same functions with ANGPT1. You can find most of the proteins on our site. Function Related Protein Function protein binding Related Protein ARHGAP17; TNF; LENG1; ZNF317; CRHR2; PGK1; MCC; NLRP2; FAM127B; FERMT2 Function receptor tyrosine kinase binding Related Protein NCK1; SHC4; SQSTM1; NRG1; DNAJA3; Flt3l; FNTA; FLT3LG; CPNE3; LRP4 https://www.creativebiomart.net/symbolsearch_ANGPT1.htm 5/6

  6. 2020/2/5 angpt1 Protein, Angiopoietin 1 - Creative BioMart Interacting Protein ANGPT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull- down and so on. We selected proteins and molecules interacted with ANGPT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ANGPT1. daap-5; TEK ANGPT1 Related Articles Mannam, VKR; Lewis, RE; et al. The fate of renal allografts hinges on responses of the microvascular endothelium. EXPERIMENTAL AND MOLECULAR PATHOLOGY 94:398-411(2013). Scotti, L; Abramovich, D; et al. Involvement of the ANGPTs/Tie-2 system in ovarian hyperstimulation syndrome (OHSS). MOLECULAR AND CELLULAR ENDOCRINOLOGY 365:223-230(2013). ANGPT1 Related Gene Family Cytokines (/gene-family-11-cytokines.htm)   45-1 Ramsey Road, Shirley, NY 11967, USA   USA: 1-631-559-9269    1-516-512-3133   Europe: 44-207-097-1828   Fax: 1-631-938-8127   Email: info@creative-biomart.com (mailto:info@creative-biomart.com) Enter your email here to subscribe. Your email address here submit Easy access to products and services you need from our library via powerful searching tools. Copyright © 2007 - 2020 Creative BioMart (/). All Rights Reserved. (https://twitter.com/CreaBiomart) (http://www.facebook.com/pages/Creative-Biomart/374357745946387) (http://www.linkedin.com/company/creative-biomart) (/blog/) https://www.creativebiomart.net/symbolsearch_ANGPT1.htm 6/6

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