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Enzyme inhibitor is a molecule which particularly binds with an enzyme to slow down its activity. It is primarily used to kill a pathogen, which produces harmful diseases to maintain the metabolic imbalance.
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Applications Forecast (2012-2022)
The enzyme inhibitor market is expected to witness growth owing to the
growth of pharmaceutical drug industry. The key driver of this industry is the
global spending on medicines in coalition with the increasing demand of
The enzyme inhibitor market is expected to witness growth owing to the growth of pharmaceutical
drug industry. The key driver of this industry is the global spending on medicines in coalition with the
increasing demand of specialty drugs. The North American region is accounted for more than 40%
market share mainly due to the presence of leading players in US pharmaceutical industry. The Asia
Pacific region is projected to see highest growth rate by 2022, particularly China is expected to witness
more than 15% CAGR in the forecasted period.
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Enzyme inhibitor is a molecule, which particularly binds with an enzyme to slow down its activity. It
is primarily used to kill a pathogen, which produces harmful diseases to maintain the metabolic
imbalance. In Agricultural industry, it is mainly used as a pesticide to attract and destroy any pest.
There are many applications of enzyme inhibitor such as chemotherapy, metabolic control, pesticides,
and natural poisons. These inhibitors alter the functioning of enzymes and thus altering the gene
expression. Few other important applications such as male erectile dysfunction, survival of bacterial
pathogens, blocking specific protein in the pancreas, regulation of neurological functioning, and
stopping toxins that pollutes environment are expected to drive the market in the near future.
Few factors that are expected to thrust the market of enzyme inhibitor are research & development
spending by pharmaceutical companies, increasing competition, and technological advancement.
Upcoming new technologies have led to the new product development, which has assisted the market
to expect high growth over the forecasted period. Sedentary lifestyle, pandemic threats, and higher
risk of disease are few other driving factors that will fuel in the growth of the market by 2022. The
key restrain that may slightly decrease the revenue growth of the market is due to the patent
expiration. Last few years patent expiration has led the pharmaceutical industry to bear revenue
losses of more than USD 20 billion each year, but from the strategic actions by pharmaceutical
companies it is projected to go down to less than one third.
The market is segmented by reversible and irreversible as per the inhibitors binding with the enzymes.
Reversible inhibitor binding with enzyme is created through non-covalent bonding such as ionic bonds
or hydrogen bonds. Non-reversible inhibitor binding with enzyme is created through covalent bonding
by reacting chemically with the enzyme.
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The market segmentation by inhibitor type into proton pump inhibitors (PPI), phosphodiesterase type
5 (PDE5) inhibitors, protease inhibitors, neuraminidase inhibitors, aromatase inhibitors, reverse
transcriptase inhibitor, statins, kinase inhibitors, and angiotensin-converting enzyme (ACE) inhibitors.
These inhibitors have varied application in the pharmaceutical industry on the basis of reaction with
the pathogens such as PPIs for reducing the long lasting production of gastric acid, PDE5 to treat the
erectile dysfunction, protease for the treatment of HIV/AIDS, kinase to block the action of protein
kinases, reverse transcriptase to generate complementary DNA, neuraminidase to block the influenza
virus, statins for reducing the cholesterol production, and angiotensin for the treatment of
The market can also be segmented by region into North America, Latin America, Europe, Asia Pacific,
and Middle East. Globally, the North America has the highest market share due to the presence of
largest players who produces the enzyme inhibitor drugs. Particularly the US has the top five largest
pharmaceutical companies based on the revenue share. In totality, it has more than 150 companies,
which are competing in the enzyme inhibitor market. Research & development spending in the US is
highest among other countries of North American region.
The European region has the second highest market share of enzyme inhibitor drugs mainly due to
the high government expenditure towards pharmaceutical industries and companies involvement in
producing the drug. Particularly in the United Kingdom, there are companies such as GlaxoSmithKline
and AstraZeneca, which accounts for maximum revenue market share of enzyme inhibitor drugs.
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The Asia Pacific region is the fastest growing market mainly due to the increasing awareness of
inhibitor drugs and increasing investment from foreign companies. Particularly the countries such as
India, China, Japan, Russia, and Singapore accounts for more than half of the market share among
other countries in the region. This is due to the high economic development, higher investments,
increasing awareness, and high population. In the forecasted period, the Asia pacific region is
expected to account for maximum share globally in at least 4-5 inhibitor drugs.
The key players that compete in the enzyme inhibitor market are Novartis, Pfizer, Roche, Sanofi,
Merch & Co., Johnson & Johnson, GlaxoSmithKline, AstraZeneca, Gilead Sciences, Takeda, Bayer,
Astellas, Daiichi Sankyo, Baxter and Novo Nordisk. Out of these companies, Novartis and Pfizer
accounts for highest revenue market share and highest R&D spending.
Geographically, this report is segmented into several key Regions, with production, consumption,
revenue (million USD), market share and growth rate of Enzyme Inhibitor in these regions, from
2012 to 2022 (forecast), covering
• North America
Global Enzyme Inhibitor market competition by top manufacturers, with production, price,
revenue (value) and market share for each manufacturer; the top players including
• Ranbaxy Laboratories
• Takeda Pharmaceuticals
• Abbott Laboratories
• Johnson and Johnson
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On the basis of product, this report displays the production, revenue, price, market share and
growth rate of each type, primarily split into
• Reversible Inhibitor
• Irreversible Inhibitor
On the basis on the end users/applications, this report focuses on the status and outlook for
major applications/end users, consumption (sales), market share and growth rate of Enzyme
Inhibitor for each application, including
• Food & Beverage
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