Multiple Endocrine Neoplasia - Symptoms, Causes, and Treatment

1. Multiple Endocrine Neoplasia - Symptoms, Causes, and Treatment - Specialty Care Clinics

2. What is Multiple Endocrine Neoplasia? Multiple endocrine neoplasia, type 1 (MEN 1), sometimes known as Wermer's syndrome, is an unusual disorder that causes tumors in the endocrine glands and parts of the small intestine and stomach. In MEN 1, the endocrine glands — generally the parathyroids, pancreas, and pituitary — grow tumors and release excessive amounts of hormones that could result in disease. Although, the tumors are generally non-cancerous (benign). The excess hormones could cause a wide variety of signs and symptoms. These could involve tiredness, bone pain, broken bones, kidney stones, and ulcers in the abdomen or intestines. MEN 1 cannot be cured. But regular testing can find out problems, and doctors can provide treatment as required. MEN 1 is a hereditary disorder. This means people who have the gene mutation could pass it on to their children. Each child has a fifty percent chance of getting the disorder.

3. Symptoms of Multiple Endocrine Neoplasia Signs and symptoms of MEN 1 are as follows:    Tiredness    Bone pain    Broken bones    Kidney stones    Ulcers in the stomach or intestines Symptoms are caused by the release of too many hormones into the body.

4. Diagnosis of Multiple Endocrine Neoplasia To diagnose multiple endocrine neoplasia, type 1 (MEN 1), your doctor will conduct a physical examination and check your medical history and family history. You might have a blood test and imaging tests, including the following:    Magnetic resonance imaging (MRI)    Computerized tomography (CT) scan    Positron emission tomography (PET) scan    Nuclear medicine scans    Endoscopic ultrasound of the pancreas and other tests

5. Genetic testing might determine whether someone has a genetic mutation causing MEN 1. If someone has a mutation, his or her children are at risk of getting the mutation and developing MEN 1. Parents and siblings also are at risk of having the mutation though they have not yet developed any symptoms. If no associated genetic changes are found in family members, then no further screening tests are required. Although, genetic testing does not uncover all MEN 1 genetic mutations. If genetic testing does not confirm MEN 1, but it is likely a person has it, that person and their family members still require close follow-up with appropriate blood and imaging tests. Continue To Read More Click Here

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