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An Effective Therapy for Wilson’s Disease

Trientine HCL is an effective therapy for the treatment of Wilson's disease. It is specifically a copper chelating agent, with a polyamine-like structure distinct from the medication penicillamine.<br>The trientine cost usually costs around 16500 INR for a supply of 100 capsules in a bottle. <br>As a chelating compound, trientine HCL is for the removal of excess copper from patients' bodies. Trientine Hydrochloride is available as 250mg capsules in order to be administered orally. Capsules of trientine hydrochloride contain gelatin, stearic acid, iron oxides, and titanium dioxide as inactive ingredi

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An Effective Therapy for Wilson’s Disease

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  1. HistoryofTrientineHydrochloride TrientineHydrochloride'ssolefunctionistoremoveheavymetalssuchaslead,mercury,andcopperfromtheblood. ThehydrochloridesaltofTETA,referredtoastrientinehydrochloride,specificallyisachelatingagent,usedinordertobindandremovecopperinthebodyforthetreatmentofWilson'sdisease,particularlyinthosewhoareintoleranttothepenicillamine. InthemonthofNovember,1985,thetrientinehydrochloride(Syprine)wasapprovedformedicaluseintheUnitedStates. InthemonthofSeptember,2017,Trientinetetrahydrochloride(Cuprior)wasapprovedformedicaluseintheEuropeanUnion. InthemonthofJuly,2019,Trientinedihydrochloride(Cufence)wasapprovedformedicaluseintheEU(EuropeanUnion). Themedicationtrientinehydrochloride250mgisindicatedinordertotreatWilson'sdiseaseinadults,adolescentsandchildren5yearsofageorolderwhoareintoleranttothetherapyofD-penicillamine. Thetrientine costinindiaisaround463,176INRforasupplyof100capsules,dependingonthewholesaler/pharmacyyouvisit.AnyWHO-GDP&ISOcertifiedpharmaceuticalwholesalercompanywouldbebesttobuytrientinehydrochloride. Source: https://www.klusster.com/portfolios/amitsharma/contents/123821

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