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IPHY 3430 3-8-11 Exam: March 15, 7:45 am Duane G1B30 .

IPHY 3430 3-8-11 Exam: March 15, 7:45 am Duane G1B30. Exchange of materials in capillaries Diffusion Bulk Flow.

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IPHY 3430 3-8-11 Exam: March 15, 7:45 am Duane G1B30 .

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  1. IPHY 3430 3-8-11Exam: March 15, 7:45 am Duane G1B30.

  2. Exchange of materials in capillariesDiffusionBulk Flow

  3. Diffusion:When the blood reaches the capillaries, many nutrients, O2, and metabolic end products diffuse out/in (down concentration gradients) between the blood and cells.Cellular utilization or production of materials causes diffusion gradient to exist between blood and cells.

  4. Bulk Flow Plasma (minus most plasma proteins) is moved by bulk flow out of the capillaries, moving all water soluble materials to the cells, and then most of the water is restored back to the circulation, carrying wastes.

  5. Fig. 10-22, p. 367

  6. Forces: Capillary blood pressure (outward) Plasma colloid osmotic pressure (inward) beginning end BP = 37 COP = 25 COP = 25 BP = 17 25-17 = 8 in 37-25 = 12 out

  7. Lymph circulation picks up the restunabsorbed “water” containing wastes, ions, etc from extracellular fluid spaceloose plasma proteinsloose red blood cellscell debrispathogenscancer cells

  8. Lymph flow caused by:1. Skeletal muscle contraction2. Smooth muscle contraction in walls of lymph vessels3. SNS stimulation to walls of lymph vessels

  9. Excretory SystemRoles:remove wastesbalance body water contentbalance body ionic contentbalance acid-base balanceKidney also regulates RBC’s and secretes renin as part of regulation of blood pressure

  10. Kidney: by regulating blood water, ionic and H+ content, can regulate extracellular fluid and cell water, ionic and H+ content blood Extracellular fluid Water, ions and H+ If blood water drops, increase blood ion content, and withdraw water from extracellular tissues, and then water would leave cell

  11. Plus,…1. adrenal gland (aldosterone)2. hypothalamus and posterior lobe of the pituitary (vasopressin)3. Heart atrium (atrial natriuretic factor)

  12. Fig. 14-3, p. 504

  13. Glomerular filtration55- (30 + 15) = 10 mm Hg BP = 55  COP = 30  blood Bowman’s Capsule 15 

  14. How glomerular filtration can be varied:Increased blood pressure65- (30 + 15) = 20 mm Hg BP = 65  COP = 30  blood Bowman’s Capsule 15 

  15. How glomerular filtration can be varied:Dehydration55- (35 + 15) = 10 mm Hg BP = 55  COP = 35  blood Bowman’s Capsule 15

  16. Materials filtered into Bowman’s capsuleWaterIonsglucose, amino acidswastes (NH3, urea, etc)a few plasma proteinseverything else in plasmahopefully no cells

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