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V5-CUG-BP1. V5-TDP-43. V5-ETR-3. Anti-V5. Anti-Hsc70. Fig. S1a. cTnT exon 5 exclusion rate. pcDNA. ETR-3. CUG-BP1. Fig. S1b. HeLa. HCT116. HGT-1. ETR-3. TDP-43. hnRNP A1. Fig. S2a. CUG-BP1. TDP-43. pcDNA. ETR-3. HCT116. HeLa. Fig. S2b. V5-CUG-BP1 + siCUG-BP1. V5-ETR-3

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V5-CUG-BP1

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V5 cug bp1

V5-CUG-BP1

V5-TDP-43

V5-ETR-3

Anti-V5

Anti-Hsc70

Fig. S1a

cTnT exon 5 exclusion rate

pcDNA

ETR-3

CUG-BP1

Fig. S1b


V5 cug bp1

HeLa

HCT116

HGT-1

ETR-3

TDP-43

hnRNP A1

Fig. S2a

CUG-BP1

TDP-43

pcDNA

ETR-3

HCT116

HeLa

Fig. S2b


V5 cug bp1

V5-CUG-BP1

+ siCUG-BP1

V5-ETR-3

+ siETR-3

V5-CUG-BP1

V5-ETR-3

Anti-V5

Anti-Hsc70

Fig. S3a

TDP-43

ETR-3

CUG-BP1

Tot

Nucl

Tot

Nucl

Tot

Nucl

Fig. S3b


V5 cug bp1

Normalised CFTR exon 9 exclusion rate

pcDNA

ETR-3

pcDNA

ETR-3

siNeg

+

+

-

-

-

-

+

+

siTDP-43

Fig. S4


V5 cug bp1

Divergent Domain

ETR-3 WT

RRM1

RRM2

RRM3

ETR-3 DD.1

ETR-3 DD.2

ETR-3 DD.3

Fig. S5


V5 cug bp1

Ctrl

ETR-3

DD.1

DD.2

DD.3

*

Fig. S6


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