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S y s t em s S k ills T ra ining. …………………… The SysMIC team. http : // sysm i c . a c . uk. CONSORTIUM. B i rl < be c k College. T he Open U n iver s i ty. T he U n i v e r sity of Edinburgh. U n i versity College London.

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SystemsSkillsTraining

……………………

TheSysMICteam

http://sysmic.ac.uk


CONSORTIUM

Birl<beck College

TheOpenUniversity

TheUniversity

ofEdinburgh

UniversityCollege

London

Expertiseinbiosciencesresearchandteaching Expertiseindistancelearning

SYsMIC


2012-2016,£1m

1,250placesover3years


SysMICCourses

Modularstructure

3modules–6monthswork –5hours/week

1:Basicskills

2:Advancedskills

3:Supervisedprojects


Mechan i st i c m ode lli ng
MechanisticModelling

Theory

Insight

Goodbiologyneedsmechanisticmodels

Numbers


TheConventionalWorkflow:


The integrat i v e w orkf l o w
TheIntegrativeWorkflow


Sysmic sess i on
SysMICsession

Materials- Tasks-Tests


SysMICExercises

Onlineversionof textbookcontains clickablesolutions


SysMICInteractiveApplet

Repressilator

Elowitz,MBandLeibler,S, Nature403(6767), 335--338(2000)


Sysmic qu i z
SysMICquiz

Self-assessment


Modu l e 1 o v e r v i e w
Module1- Overview

  • Basic MatLab

  • Networks

  • Modelling

  • Sta6s6cs


SysMIC TrainingApproach

Classical


SysMIC TrainingApproach

  • Starting Point: Biological Question

  • Are two AA sequences similar? (Context: homologs)


Training Outcomes

Network Analysis


TrainingAssessment

Quizz


Job Opportunities

7

BiotechIndustry:Predictingmicrobialfluxes


Job Opportunities

7

PharmaIndustry:DesigningCombinatorialTherapies


Job Opportunities

7

Medicine:PathologicalNetworkControl


SystemsSkillsTraining

……………………

TheSysMICteam

[email protected]