1 / 23

GI pathophysiology Review section - PowerPoint PPT Presentation

  • Uploaded on

GI pathophysiology Review section. Bios E-162b, Dec 5, 2010. Overview of the GI system. Transit of foodstuffs through the GI system. The wall of the GI tract has several layers.

I am the owner, or an agent authorized to act on behalf of the owner, of the copyrighted work described.
Download Presentation

PowerPoint Slideshow about ' GI pathophysiology Review section' - zandra

An Image/Link below is provided (as is) to download presentation

Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.

- - - - - - - - - - - - - - - - - - - - - - - - - - E N D - - - - - - - - - - - - - - - - - - - - - - - - - -
Presentation Transcript

GI pathophysiology

Review section

Bios E-162b, Dec 5, 2010

Overview of the GI system

Transit of foodstuffs through the GI system

Bile and pancreatic secretions are emptied at the same point in the duodenum

The enteric nervous system regulates GI activity in the duodenum

GI hormones also regulate GI activity in the duodenum

Gastroesophageal in the duodenum reflux is due to an insufficient closure of the lower esophageal sphincter

Hiatus hernias may also cause in the duodenumgastroesophageal reflux

Several factors may cause or aggravate GER in the duodenum

  • Young age

  • Obesity

  • Pregnancy

  • Postural changes after eating

  • - Smoking

  • - Peppermint, coffee, alcohol

  • - Diseases of connective tissue

GER may lead to Barrett’s esophagus in the duodenum

Gastric metaplasia of the esophageal epithelium

Barrett’s esophagus mat lead to esophageal in the duodenumadenocarcinoma

H. + HCO3Pilori is the most common cause

H. + HCO3Pilori is the most common cause

The digestion of carbohydrates + HCO3

Most dietary carbs are polysaccharides

Cooper GM. The Cell: A Molecular Approach. 2nd edition.

The digestion of carbohydrates + HCO3

Allcarbohydrates are convertedtomonosaccharidesbeforeabsorption

salivary a-amilase

5% starch


salivary a-amilase

25% starch





The digestion of carbohydrates + HCO3

Disaccharidases at intestinal villitransformdisaccharides in monosaccharides

The digestion of fats + HCO3

Types of diarrhea + HCO3


ie. Lactose intolerance


ie. Cholera


ie. Celiac disease


ie. Chron’s disease

High motility

ie. Some medications