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GI pathophysiology Review section. Bios E-162b, Dec 5, 2010. Overview of the GI system. http://en.wikipedia.org/wiki/File:Digestive_system_diagram_edit.svg. Transit of foodstuffs through the GI system. http://www.youtube.com/watch?v=Z7xKYNz9AS0. The wall of the GI tract has several layers.

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Gi pathophysiology review section

GI pathophysiology

Review section

Bios E-162b, Dec 5, 2010


Gi pathophysiology review section

Overview of the GI system

http://en.wikipedia.org/wiki/File:Digestive_system_diagram_edit.svg


Gi pathophysiology review section

Transit of foodstuffs through the GI system

http://www.youtube.com/watch?v=Z7xKYNz9AS0


Gi pathophysiology review section

The wall of the GI tract has several layers


Gi pathophysiology review section

Sphincters control the transit from one section of the GI tract to the next

www.mydr.com.au


Gi pathophysiology review section

Bile and pancreatic secretions are emptied at the same point in the duodenum

www.memorialhermann.org


Gi pathophysiology review section

The enteric nervous system regulates GI activity

mikedaisey.com


Gi pathophysiology review section

GI hormones also regulate GI activity

04340.com


Gi pathophysiology review section

Gastroesophageal reflux is due to an insufficient closure of the lower esophageal sphincter

www.webmd.com


Gi pathophysiology review section

Hiatus hernias may also cause gastroesophageal reflux

myhealth.ucsd.edu


Gi pathophysiology review section

Several factors may cause or aggravate GER

  • Young age

  • Obesity

  • Pregnancy

  • Postural changes after eating

  • - Smoking

  • - Peppermint, coffee, alcohol

  • - Diseases of connective tissue


Gi pathophysiology review section

GER may lead to Barrett’s esophagus

Gastric metaplasia of the esophageal epithelium

www.lwjuan.com


Gi pathophysiology review section

Barrett’s esophagus mat lead to esophageal adenocarcinoma

upload.wikimedia.org


Gi pathophysiology review section

The stomach mucosa produces acid, mucus and pepsinogen


Gi pathophysiology review section

Several mediators induce acid secretion


Gi pathophysiology review section

Peptic ulcers come from an imbalance between acid vs. mucus + HCO3

www.yourgicenter.com


Gi pathophysiology review section

H. Pilori is the most common cause

bioweb.uwlax.edu


Gi pathophysiology review section

H. Pilori is the most common cause

upload.wikimedia.org


Gi pathophysiology review section

The digestion of carbohydrates

Most dietary carbs are polysaccharides

Cooper GM. The Cell: A Molecular Approach. 2nd edition.


Gi pathophysiology review section

The digestion of carbohydrates

Allcarbohydrates are convertedtomonosaccharidesbeforeabsorption

salivary a-amilase

5% starch

Maltose

salivary a-amilase

25% starch

Maltose

pancreatica-amilase

70%starch

Maltose


Gi pathophysiology review section

The digestion of carbohydrates

Disaccharidases at intestinal villitransformdisaccharides in monosaccharides


Gi pathophysiology review section

The digestion of fats

web.campbell.edu


Gi pathophysiology review section

Types of diarrhea

Osmotic

ie. Lactose intolerance

Secretory

ie. Cholera

Malabsoptive

ie. Celiac disease

Inflammatory

ie. Chron’s disease

High motility

ie. Some medications


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