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GI pathophysiology Review section. Bios E-162b, Dec 5, 2010. Overview of the GI system. http://en.wikipedia.org/wiki/File:Digestive_system_diagram_edit.svg. Transit of foodstuffs through the GI system. http://www.youtube.com/watch?v=Z7xKYNz9AS0. The wall of the GI tract has several layers.

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GI pathophysiology

Review section

Bios E-162b, Dec 5, 2010


Overview of the GI system

http://en.wikipedia.org/wiki/File:Digestive_system_diagram_edit.svg


Transit of foodstuffs through the GI system

http://www.youtube.com/watch?v=Z7xKYNz9AS0




Bile and pancreatic secretions are emptied at the same point in the duodenum

www.memorialhermann.org


The enteric nervous system regulates GI activity in the duodenum

mikedaisey.com


GI hormones also regulate GI activity in the duodenum

04340.com


Gastroesophageal in the duodenum reflux is due to an insufficient closure of the lower esophageal sphincter

www.webmd.com


Hiatus hernias may also cause in the duodenumgastroesophageal reflux

myhealth.ucsd.edu


Several factors may cause or aggravate GER in the duodenum

  • Young age

  • Obesity

  • Pregnancy

  • Postural changes after eating

  • - Smoking

  • - Peppermint, coffee, alcohol

  • - Diseases of connective tissue


GER may lead to Barrett’s esophagus in the duodenum

Gastric metaplasia of the esophageal epithelium

www.lwjuan.com


Barrett’s esophagus mat lead to esophageal in the duodenumadenocarcinoma

upload.wikimedia.org





H. + HCO3Pilori is the most common cause

bioweb.uwlax.edu


H. + HCO3Pilori is the most common cause

upload.wikimedia.org


The digestion of carbohydrates + HCO3

Most dietary carbs are polysaccharides

Cooper GM. The Cell: A Molecular Approach. 2nd edition.


The digestion of carbohydrates + HCO3

Allcarbohydrates are convertedtomonosaccharidesbeforeabsorption

salivary a-amilase

5% starch

Maltose

salivary a-amilase

25% starch

Maltose

pancreatica-amilase

70%starch

Maltose


The digestion of carbohydrates + HCO3

Disaccharidases at intestinal villitransformdisaccharides in monosaccharides


The digestion of fats + HCO3

web.campbell.edu


Types of diarrhea + HCO3

Osmotic

ie. Lactose intolerance

Secretory

ie. Cholera

Malabsoptive

ie. Celiac disease

Inflammatory

ie. Chron’s disease

High motility

ie. Some medications


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