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GI pathophysiology Review section. Bios E-162b, Dec 5, 2010. Overview of the GI system. http://en.wikipedia.org/wiki/File:Digestive_system_diagram_edit.svg. Transit of foodstuffs through the GI system. http://www.youtube.com/watch?v=Z7xKYNz9AS0. The wall of the GI tract has several layers.

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slide1

GI pathophysiology

Review section

Bios E-162b, Dec 5, 2010

slide2

Overview of the GI system

http://en.wikipedia.org/wiki/File:Digestive_system_diagram_edit.svg

slide3

Transit of foodstuffs through the GI system

http://www.youtube.com/watch?v=Z7xKYNz9AS0

slide9

Gastroesophageal reflux is due to an insufficient closure of the lower esophageal sphincter

www.webmd.com

slide11

Several factors may cause or aggravate GER

  • Young age
  • Obesity
  • Pregnancy
  • Postural changes after eating
  • - Smoking
  • - Peppermint, coffee, alcohol
  • - Diseases of connective tissue
slide12

GER may lead to Barrett’s esophagus

Gastric metaplasia of the esophageal epithelium

www.lwjuan.com

slide19

The digestion of carbohydrates

Most dietary carbs are polysaccharides

Cooper GM. The Cell: A Molecular Approach. 2nd edition.

slide20

The digestion of carbohydrates

Allcarbohydrates are convertedtomonosaccharidesbeforeabsorption

salivary a-amilase

5% starch

Maltose

salivary a-amilase

25% starch

Maltose

pancreatica-amilase

70%starch

Maltose

slide21

The digestion of carbohydrates

Disaccharidases at intestinal villitransformdisaccharides in monosaccharides

slide22

The digestion of fats

web.campbell.edu

slide23

Types of diarrhea

Osmotic

ie. Lactose intolerance

Secretory

ie. Cholera

Malabsoptive

ie. Celiac disease

Inflammatory

ie. Chron’s disease

High motility

ie. Some medications

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