Option D. D.8 drug action. Some aspects of molecular structure that affect drug action . stereo isomerism geometric ( cis /trans) optical isomerism ( enantiomers ) s train in ring structure molecular polarity ( solubility and uptake).
D.8 drug action
cannot act as an antic-cancer drug as nitrogen atoms are too far apart to react with DNA – no pharmaceutical effect
Inorganic transition complex with a square planar shape, 900 bond angles and dative covalent bonds
Carbon atoms in ring structures can also be chiral if the part of the ring on one side of the carbon atom is different from the part of the ring on the other side of the carbon atom.
Each side of a ring is classified a different group if, when moving around the ring from the chiral centre, the order of atoms is different each way. It is said the chiral atom has two different views around the ring.
Identify the chiral carbon in the structure below
a four-membered square ring structure which contains an amide group
(-CONH-) and consists of one nitrogen atom and three carbon atoms (and two hydrogen atoms).
Both hydroxyl groups replaced by ester groups