Inactivated Influenza Vaccine Administration via Microneedle Patch; a Novel Vaccine Delivery System. Karen Mask, RN, BSN MPH Candidate April 11, 2014. Background. Seasonal influenza leads to significant morbidity & mortality each year. Worldwide: 3 to 5 million cases of severe illness
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Inactivated Influenza Vaccine Administration via Microneedle Patch; a Novel Vaccine Delivery System
Karen Mask, RN, BSN
April 11, 2014
Microneedle patch pre-clinical studies
(working title - in development)
Drs. Nadine Rouphael and Mark Mulligan
and Bioengineering (NIBIB)
Centers for Disease Control and Prevention. (2013). National early season flu vaccination coverage, United States. Retrieved March 30, 2014 from http://www.cdc.gov/flu/fluvaxview/nifs-estimates-nov2013.htm
Norman, J.J., Arya, J.M., McClain, M.A., Frew, P.M., Meltzer, M.I., & Prausnitz, M.R. (2014). Microneedle patches: Usability and acceptability for self-vaccination against influenza. Vaccine, 32(16), 1856-1862.
Thompson, W.W. (2004). Influenza-associated hospitalizations in the United States. Journal of the American Medical Association, 292(11), 1333-1340.
World Health Organization. (2009, April). Influenza (Seasonal). WHO Fact Sheet, 211.
Zhu, Q., Zarnitsyn, V.G., Ye, L., Wen, Z, Gao, Y., Pan, L., Skountzou, I., et al. (2009). Immunization by vaccine-coated microneedle arrays protects against lethal influenza challenge. Proceedings of the National Academy of Sciences of the United States of America, 106(19), 7968-7973.