This presentation is the property of its rightful owner.
Sponsored Links
1 / 38

老人の薬物 PowerPoint PPT Presentation


  • 87 Views
  • Uploaded on
  • Presentation posted in: General

老人の薬物. 16 班: 奥薗                       重田                      松田                     突田                      高野                        指導:村上先生. Case history. 79 才女性 消化管の内視鏡検査予定 内視鏡検査時、精神安定のためジアゼパム  2mg投与 五分後症状改善せず さらに5mgジアゼパム投与 検査後呼吸困難とチアノーゼ様相表れる その後ICUへ. ベンゾジアゼピン系の作用機序.

Download Presentation

老人の薬物

An Image/Link below is provided (as is) to download presentation

Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.


- - - - - - - - - - - - - - - - - - - - - - - - - - E N D - - - - - - - - - - - - - - - - - - - - - - - - - -

Presentation Transcript


3275545

16


Case history

Case history

  • 79


3275545

GABAGABAA

Cl channel Cl


3275545

GABAA,

GABAA


3275545


3275545

(

  • case history)


3275545

COPD


3275545

(99%


3275545

  • (

  • (

    biotransformation


Biotransformation

biotransformation

Biotransformation()

prodrug


3275545

cytocrome P450)


3275545

ClH

M = Q ( Ci Co )

M :

Q :

Ci :

Co:

MCiClH

ClHQ ( Ci Co ) / Ci


3275545

  • (


3275545

  • 180 /

  • (Ex.Penicillin)


3275545

C l p=UP/C p

C l p :

:

P :

C p :

(GFR)(clearance ratio)11


3275545


3275545

pH

pH


3275545


3275545

Vd

  • Lean body mass

  • VdVdV

    distribution


3275545

1520


Aag 1 acid glycoprotein

AAG(1 Acid Glycoprotein)

AAG

AAGAAGVd


3275545

AAGVdVdAAGVd


3275545


3275545


3275545

(AUC)


3275545


3275545


3275545


3275545

(

Cl({140 (}IBW

Cl( 72C(ms/dl)

Cl(0.85

Cl :(ml/

IBW :

C :/


3275545


3275545


3275545


3275545


3275545


  • Login