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If you are primarily storing documents, then a Native XML Database may be the best option. However it will depend on document structure and on the kinds of questions you need to ask about the information / data that the documents contain.
If you have a heavy investment in an Object-Relational DBMS their XML add-on support may be appropriate. If you are starting from scratch, the Native XML DBMSs are generally cheaper, lighter, and easier to manage.
Referential integrity is at the core of the relational model.
In XML the concept of integrity is less well defined and application code will be required to maintain integrity.
If there is a strong requirement for data integrity, then a relational or XML enabled database may be the better solution.
When mapping an XML document into a relational database (if you're not using a BLOB to store the whole document), some information about the document will be lost. If you require that data must retain its original structure, into and out of storage, then an Native XML Database is the best solution.