Clinical trials

1. Clinical trials Virtual tour Draft 2/19

2. Clinical Trials: Integrating with patient care Adobe BerdyMedical Carefx CommerceNet DCRI Dictaphone Digital Infuzion Eclipsys Epic GE Medical Systems Heartlab IBM INFINITT Kodak Kryptiq Microsoft Misys Mortara NIST Philips Medical Systems Raining Data Sentillion Siemens SNOMED XIMIS Imaging aECG Arden CCOW CDA CT EUA ODM PIX PSA RID RIM SDM SPL SWF V2 V3 Hospital PCP FDA Hospital Central Lab Core Lab Sponsor Patients seen at PCP, hospitals ECGs sent to Core Lab; annotated on site or at Core Lab

3. Clinical Trials: Integrating with patient care Adobe Berdy Medical Carefx CommerceNet DCRI Dictaphone Digital Infuzion Eclipsys Epic GE Medical Systems Heartlab IBM INFINITT Kodak Kryptiq Microsoft Misys Mortara NIST Philips Raining Data Sentillion Siemens SNOMED XIMIS aECG Arden CCOW CDA CT EUA ODM PIX PSA RID RIM SDM SPL SWF V2 V3 Imaging Hospital PCP Query broker, trusted 3rd party FDA Hospital Repository ? Registry Central Lab Core Lab Sponsor Patients seen at PCP, hospitals ECGs sent to Core Lab; annotated on site or at Core Lab

4. Clinical Trials: Integrating with patient care Adobe Berdy Medical Carefx CommerceNet DCRI Dictaphone Digital Infuzion Eclipsys Epic GE Medical Systems Heartlab IBM INFINITT Kodak Kryptiq Microsoft Misys Mortara NIST Philips Raining Data Sentillion Siemens SNOMED XIMIS aECG Arden CCOW CDA CT EUA ODM PIX PSA RID RIM SDM SPL SWF V2 V3 Patients seen at PCP, hospitals ECGs sent to Core Lab; annotated on site or at Core Lab

5. Clinical Trials: Integrating with patient care Adobe Berdy Medical Carefx CommerceNet DCRI Dictaphone Digital Infuzion Eclipsys Epic GE Medical Systems Heartlab IBM INFINITT Kodak Kryptiq Microsoft Misys Mortara NIST Philips Raining Data Sentillion Siemens SNOMED XIMIS aECG Arden CCOW CDA CT EUA ODM PIX PSA RID RIM SDM SPL SWF V2 V3 Patients seen at PCP, hospitals ECGs sent to Core Lab; annotated on site or at Core Lab

6. Clinical Trials: Integrating with patient care Adobe Berdy Medical Carefx CommerceNet DCRI Dictaphone Digital Infuzion Eclipsys Epic GE Medical Systems Heartlab IBM INFINITT Kodak Kryptiq Microsoft Misys Mortara NIST Philips Raining Data Sentillion Siemens SNOMED XIMIS aECG Arden CCOW CDA CT EUA ODM PIX PSA RID RIM SDM SPL SWF V2 V3 [sb aECG w/annotations; is ODM] Intervals for Analysis imported into Clinical Data Management System at Core Lab

7. Clinical Trials: Integrating with patient care Adobe Berdy Medical Carefx CommerceNet DCRI Dictaphone Digital Infuzion Eclipsys Epic GE Medical Systems Heartlab IBM INFINITT Kodak Kryptiq Microsoft Misys Mortara NIST Philips Raining Data Sentillion Siemens SNOMED XIMIS aECG Arden CCOW CDA CT EUA ODM PIX PSA RID RIM SDM SPL SWF V2 V3 LDM data Interval Data for Analysis written in CDISC SDM and ODM for delivery to Sponsor

8. Clinical Trials: Integrating with patient care Adobe Berdy Medical Carefx CommerceNet DCRI Dictaphone Digital Infuzion Eclipsys Epic GE Medical Systems Heartlab IBM INFINITT Kodak Kryptiq Microsoft Misys Mortara NIST Philips Raining Data Sentillion Siemens SNOMED XIMIS aECG Arden CCOW CDA CT EUA ODM PIX PSA RID RIM SDM SPL SWF V2 V3 Interval Data for Analysis written in CDISC SDM and ODM for delivery to Sponsor

9. Clinical Trials: Integrating with patient care Adobe Berdy Medical Carefx CommerceNet DCRI Dictaphone Digital Infuzion Eclipsys Epic GE Medical Systems Heartlab IBM INFINITT Kodak Kryptiq Microsoft Misys Mortara NIST Philips Raining Data Sentillion Siemens SNOMED XIMIS aECG Arden CCOW CDA CT EUA ODM PIX PSA RID RIM SDM SPL SWF V2 V3 Patients seen at PCP, hospitals ECGs sent to Core Lab; annotated on site or at Core Lab

10. Clinical Trials: Integrating with patient care Adobe Berdy Medical Carefx CommerceNet DCRI Dictaphone Digital Infuzion Eclipsys Epic GE Medical Systems Heartlab IBM INFINITT Kodak Kryptiq Microsoft Misys Mortara NIST Philips Raining Data Sentillion Siemens SNOMED XIMIS aECG Arden CCOW CDA CT EUA ODM PIX PSA RID RIM SDM SPL SWF V2 V3 Sample SDM Patients seen at PCP, hospitals ECGs sent to Core Lab; annotated on site or at Core Lab

11. Clinical Trials: Integrating with patient care Adobe Berdy Medical Carefx CommerceNet DCRI Dictaphone Digital Infuzion Eclipsys Epic GE Medical Systems Heartlab IBM INFINITT Kodak Kryptiq Microsoft Misys Mortara NIST Philips Raining Data Sentillion Siemens SNOMED XIMIS aECG Arden CCOW CDA CT EUA ODM PIX PSA RID RIM SDM SPL SWF V2 V3 Sample SDM Screen shot of patient profile viewer Patients seen at PCP, hospitals ECGs sent to Core Lab; annotated on site or at Core Lab

12. Clinical Trials: Integrating with patient care Adobe BerdyMedical Carefx CommerceNet DCRI Dictaphone Digital Infuzion Eclipsys Epic GE Medical Systems Heartlab IBM INFINITT Kodak Kryptiq Microsoft Misys Mortara NIST Philips Medical Systems Raining Data Sentillion Siemens SNOMED XIMIS PCP aECG Arden CCOW CDA CT EUA ODM PIX PSA RID RIM SDM SPL SWF V2 V3 Hospital Imaging FDA Hospital Core Lab Lab Sponsor Patients seen at PCP, hospitals ECGs sent to Core Lab; annotated on site or at Core Lab

13. Clinical Trials: Integrating with patient care Adobe Berdy Medical Carefx CommerceNet DCRI Dictaphone Digital Infuzion Eclipsys Epic GE Medical Systems Heartlab IBM INFINITT Kodak Kryptiq Microsoft Misys Mortara NIST Philips Raining Data Sentillion Siemens SNOMED XIMIS aECG Arden CCOW CDA CT EUA ODM PIX PSA RID RIM SDM SPL SWF V2 V3 PCP Hospital Imaging Query broker, trusted 3rd party FDA Hospital Repository ? Registry Lab Core Lab Lab Sponsor Patients seen at PCP, hospitals ECGs sent to Core Lab; annotated on site or at Core Lab