CNS – Antiepileptic Drugs. Compare and contrast the terms seizure, convulsion and epilepsy. Discuss the indications for antiepileptic therapy (AED). Compare and contrast the first line drugs of choice for AED.
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Terms overlap and are used interchangeably to achieve the goal of maintaining a reasonable quality of life.
1. Increase threshold of activity in the motor cortex
Makes it more difficult to excite; reduces response
2. Depress the seizure discharge from its origin
Suppress transmission of impulsesfrom one nerve to the next
3. Decrease the speed of nerve impulse conduction within a given neuron
clorazepate (Tranxene), lorazepam (Ativan)
to go to the bathroom.