1 / 23

Epicardial Mapping from Intracoronary Catheters

Epicardial Mapping from Intracoronary Catheters. Rob MacLeod, Richard Kuenzler, Quan Ni, Bruno Taccardi, and Bob Lux. NEH Cardiovascular Research and Training Institute (CVRTI), U of Utah. Cardiac Mapping. Coverage Surface or volume Sampling Density. Epicardial Endocardial Venous.

yardley-hoover
Download Presentation

Epicardial Mapping from Intracoronary Catheters

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Epicardial Mapping from Intracoronary Catheters Rob MacLeod, Richard Kuenzler, Quan Ni, Bruno Taccardi, and Bob Lux NEH Cardiovascular Research and Training Institute (CVRTI), U of Utah

  2. Cardiac Mapping • Coverage • Surface or volume • Sampling Density

  3. Epicardial Endocardial Venous Catheter Mapping

  4. The Questions • What are catheter electrograms? • Can they provide mapping data?

  5. Catheter Measurements • Acute dog preparation • Cardima 4-16 pole catheters • High resolution epicardial plaque

  6. Catheter Epi 1 Epi 2 Electrogram Comparison 20 10 V [mV] 0 -10 -20 -30 -40

  7. Statistical Comparison

  8. 42 electrodes Interpolation Original Hardy’s Laplacian

  9. 42 electrodes Interpolation Original Hardy’s Laplacian

  10. Training Data Covariance Matrix Sub-sampled Data Estimate = * Estimation Matrix Statistical Estimation

  11. Interpolation vs. Estimation Statistical Estimation Original Hardy’s Laplacian

  12. Interpolation vs. Estimation Statistical Estimation Original Hardy’s Laplacian

  13. Electrode Spacing Original Estimated: 41 leads (4 mm spacing) Estimated: 21 leads (8 mm spacing)

  14. Test Geometry GCV CS GCV Coronary Circulation MCV LVP Surrogate Catheters

  15. Indicator of database quality Resubstitution Protocol Training Data Test Data Experiment 1 Experiment 3 Experiment 2 Experiment 4

  16. Intermittent bad lead case Leave-One-Map-Out Protocol Training Data Test Data Experiment 1 Experiment 3 Experiment 2 Experiment 4

  17. Experiment 3 • Clinically relevant case Leave-One-Experiment-Out Protocol Training Data Test Data Experiment 1 Experiment 2 Experiment 4

  18. Original Resubstitution Leave Out One Map Leave Out One Experiment LV Pacing

  19. Original Resubstitution Leave Out One Map Leave Out One Experiment Anterior Pacing

  20. Original Resubstitution Leave Out One Map Leave Out One Experiment Apical Pacing

  21. Original Resubstitution Leave Out One Map Leave Out One Experiment Posterior Pacing

  22. Effect of # of Leads Relative Error Mean • leads evenly spaced • N=153 maps L-experiment L-map Resubstitution Std. Dev. 5 10 15 20 25 30 35 40 # Catheter Leads

  23. Current Research • Acquire larger database • Variety of activation sequences • Range of interventions • Evaluate other estimation approaches • Evaluate other basis functions • Merge estimation with interpolation

More Related