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3526 patients

GALA. 95 centres. 24 countries. 3526 patients. Austria Australia Belarus China Croatia Czech Republic Estonia Georgia Germany Greece Hungary Israel. Italy Latvia Netherlands Poland Portugal Saudi Arabia Slovakia Spain Sweden Turkey

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3526 patients

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  1. GALA 95centres 24countries 3526 patients

  2. Austria Australia Belarus China Croatia Czech Republic Estonia Georgia Germany Greece Hungary Israel Italy Latvia Netherlands Poland Portugal Saudi Arabia Slovakia Spain Sweden Turkey UK Ukraine Countries & Centres

  3. Background Is it time for a randomized trial of local versus general anaesthesia for carotid endarterectomy? M. J. Gough, T. A. J. Calvey, A. J. McCleary, S. Whitely, A.Bodenham Leeds, UK Non-randomized, patients had a free choice of the type of anaesthetic. LA GA N=89 N=101* 30-day stroke rate 0 (0) 4 (4) Perioperative MI 1 (1) 3 (3) Death 1 (1) 2 (2) *P=0·057 versus LA P=0·046 versus LA for combined stroke/MI These results reinforce the need for a prospective, randomized trial.

  4. Introduction Eur J Vasc Endovasc Surg 13, 491-499 (1997) Local Versus General Anaesthesia in Carotid Endarterectomy: a Systematic Review of the Evidence C. Tangkanakul, C. E. Counsell and C. P. Warlow Neurosciences Trials Unit, Department of Clinical Neurosciences, Western General Hospital, Edinburgh, U.K. • Eur J Vasc Endovasc Surg 12, 173-181 (1996) • The Differing Effects of Regional and General Anaesthesia on • Cerebral Metabolism During Carotid Endarterectomy* • J. McCleary, N. M. Dearden, D. H. Dickson, A. Watson • M. J. Gough • Departments of Vascular Surgery and Anaesthetics, The General Infirmary, Leeds, U.K.

  5. What Happened Next? CPW, MJG Steering Committee Protocol MREC Trial Co-ordinator Funding Pilot: 20 UK Centres

  6. Pilot study completed MREC approval for main trial Funding: Health Foundation ESVS Centre recruitment: Journal adverts Vascular Society Charing Cross European Meetings Trial Office: Bridget Colam Anne Fraser Steff Lewis Mary Paterson Vera Soosay Adam Young Trial Steering Committee Data Monitoring Committee GALA - continued

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