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白细胞分化抗原和黏附分子 PowerPoint PPT Presentation


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第7章. 白细胞分化抗原和黏附分子. (Leukocyte differentiation antigen & cell adhesion molecules,CAM). §1.免疫细胞表面功能分子和人白细胞分化抗原. § 2. 粘附分子 §3. CD 分子和黏附分子 及其单抗的临床应用. 一.免疫细胞表面功能分子. 1 . 受体( receptors ). 2. 细胞表面分子 (cell surface molecules). (Functional molecules on surface of immune cell). (1) 识别受体.

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白细胞分化抗原和黏附分子

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3407919

7

(Leukocyte differentiation antigen & cell adhesion molecules,CAM)


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1.

2.

3.CD


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.

.receptors

2.

(cell surface molecules)

(Functional molecules on surface of immune cell)


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(1)


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(2)


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*

CD**


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.

lineage


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2.

1

2

3GPI


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.


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.CD

cluster of differentiation

CD


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2.

(Cell Adhesion Molecules,CAM)


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Introduction

1.


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2.

  • -


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3.

(1)integrin family

(2)(IgSF)

(3)(selectin family)

(4)(cadherin family)

(5)

(6)


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.integrin family

.(selectin family)

.CAM


Integrin family

integrin family

1.

2.1488


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  • 3.


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B

T


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  • 1.CCLEGFCL

  • 2.LPE

  • 3.


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  • 1.

  • 2.

  • 3.


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Th cell

TCR

CD4

2

MHC class II

APC


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L E CD15s


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3.CD


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