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Drill #2 2/24/10. From last night’s reading you learned that traits in families can be tracked through the generations. Please describe why you think this is an important practice. Pedigrees?. Or. A Little Bit of Vocab…. Pedigree :

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Drill 2 2 24 10
Drill #22/24/10

  • From last night’s reading you learned that traits in families can be tracked through the generations. Please describe why you think this is an important practice.



A little bit of vocab
A Little Bit of Vocab….

  • Pedigree:

    A tool used to determine how one particular trait is inherited

  • Wild-Type:

    Phenotype that appears most often in the population


Trait inheritance
Trait Inheritance

  • Traits can be inherited on either Autosomes or Sex Chromosomes

Which Sex Chromosome do you think has more genetic disorders found on it?


Autosomal inheritance
Autosomal Inheritance

  • Autosomal Recessive:

    • Caused by presence of two recessive alleles (dd)

    • There are “Carriers” – (Dd)

      • Do not have the trait, but contain a copy of the allele

    • Usually does not show up in all generations (skips)

Cystic Fibrosis

Albinism




Autosomal inheritance1
Autosomal Inheritance

  • Autosomal Dominant:

    • Any copy of a dominant allele will result in the disorder (DD or Dd)

    • There are no carriers – Why?

      • A person with Dd has the disorder!

Achondroplasia

Webbed-Toes

Polydactyly



Why are most lethal Dominant alleles uncommon?

Usually, autosomal traits show up in 50% males/50% females, why?


Sex linked
Sex Linked

  • X-Linked Recessive:

    • Must have only recessive copies of the allele

    • Female = XdXd – Must have both copies

    • Male = XdY– Only needs one copy

Fruit Flies – White Eyes

Color-Blindness

Hemophilia


Female “Carriers”

Males have trait


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