BIPN 148 Lecture 14
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BIPN 148 Lecture 14. Biochemical Basis of LTP. Spatial learning induces gene expression. Calcium regulation of gene expression. CaM Kinase IV activates CREB. CaM Kinase IV phosphorylates CREB. LTP in dnCKIV mice. dnCaMKIV suppresses fear conditioning. Spatial learning in dnCKIV mice.

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BIPN 148 Lecture 14

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BIPN 148 Lecture 14


Biochemical Basis of LTP


Spatial learning induces gene expression


Calcium regulation of gene expression


CaM Kinase IV activates CREB


CaM Kinase IV phosphorylates CREB


LTP in dnCKIV mice


dnCaMKIV suppresses fear conditioning


Spatial learning in dnCKIV mice


Impaired LTP in CKIV null mice


LTP in CKIV null mice


Calmodulin translocation in CKIV null mice


Fear conditioning in CKIV null mice


CREB phosphorylation in CKIV null mice


CREB phosphorylation in CKIV null mice


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