Emily brown advisor dr gary bledsoe be@slu reu summer 2009 saint louis university
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Emily Brown Advisor: Dr. Gary Bledsoe [email protected] REU, Summer 2009 Saint Louis University. Biomechanical Testing of the Lumbar Intervertebral Discs. Background. Lumbar spine Contains 5 vertebrae Highest loads Most prone to degenerative disc disease.

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Emily brown advisor dr gary bledsoe be@slu reu summer 2009 saint louis university

Emily Brown

Advisor: Dr. Gary Bledsoe

[email protected] REU, Summer 2009

Saint Louis University

Biomechanical Testing of the Lumbar Intervertebral Discs


Background
Background

  • Lumbar spine

    • Contains 5 vertebrae

    • Highest loads

    • Most prone to degenerative disc disease

From: http://www.backpain-guide.com/Chapter_Fig_folders/Ch05_Anatomy_Folder/Ch5_Images/05-4_Overall_Spine.jpg


Intervertebral disc anatomy
Intervertebral Disc Anatomy

  • Annulus Fibrosus

  • Nucleus Pulposus

  • Vertebral End Plate

From: http://indyspinemd.com/Images/normalAnat/IntervertebralDisc.jpg



Intervertebral disc biomechanics
Intervertebral Disc Biomechanics

  • Compression

    • Failure of end plate

  • Torsion

    • Most damaging to disc

  • Degenerated Discs

    • Lower load to failure

From: http://www.biomechanika.cz/index.php?lang=en&pg=laborator-mechanickych-zkousek


Lab goals
Lab Goals

  • Study biomechanical properties of orthopedics

    • Orthopedic devices

      • Plate fixators

      • Interbody spinal fusion cages

    • Spine

      • Intact lumbar segment

      • Individual intervertebral discs


Rationale
Rationale

  • Methodology for use on fresh lumbar spines

    • More accurate model for in vivo studies

  • Finite element model

  • Degenerative disc disease

    • Comparing normal tested discs to patients' discs


Intervertebral disc project
Intervertebral Disc Project

  • Mechanical Testing

    • Compressional

    • Torsional

    • Compressional/Torsional Combination

  • Analysis


Methods and materials
Methods and Materials

  • MTS

    • Testing

    • Collection of data

  • Discs from 3 human cadavers

    • L1-L2 through L4-L5


Specific goals
Specific Goals

  • Grip system for discs in testing

  • Measure biomechanical properties

    • Stress v strain

    • Elastic modulus

  • Determine effects of formalin fixation on disc properties


References
References

  • Farafan HF, Cossette JW, Robertson GH, Wells RV, Kraus H: The Effects of Torsion on the Lumbar Intervertebral Joints: The Role of Torsion in the Production of Disc Degeneration. J. Bone and Joint Surg., 52: 468-497, 1970

  • Nixon J: Intervertebral disc mechanics: a review. Journal of the Royal Society of Medicine, v79(2): 100-104, February 1986

  • Panjabi M, White A: Basic Biomechanics of the Spine. J of Neurosurgery, 7(1): 76-93, 1980

  • Urban J, Roberts S: Degeneration of the intervertebral disc. Arthritis Research and Therapy, v5(3): 120-130, March 2003

  • Wilke H, Krischak S, Claes L: Formalin Fixation Strongly Influences Biomechanical Properties of the Spine



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