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Growth and development. Samir Najjar M.D Professor, Department of Pediatrics. Stages of growth and development. Intrauterine Infancy Childhood Adolescence Adulthood. Intrauterine Growth. Greatest length velocity at mid fetal life Development of adipose tissue at 7 months

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growth and development

Growth and development

Samir Najjar M.D

Professor, Department of Pediatrics

stages of growth and development
Stages of growth and development
  • Intrauterine
  • Infancy
  • Childhood
  • Adolescence
  • Adulthood
intrauterine growth
Intrauterine Growth
  • Greatest length velocity at mid fetal life
  • Development of adipose tissue at 7 months
  • weight doubles in the last 2 months
  • Weight loss beyond 40 weeks
constrains on intrauterine growth
Constrains on intrauterine growth
  • Uterine size
  • Placenta
  • Size of the mother
infancy
Infancy
  • The era of changing growth rate
childhood
Childhood
  • The era of stable growth rate
adolescence
Adolescence
  • The era of sex hormone induced shifting growth
slide25

CLASSIFICATION OF SHORT STATURE

SHORT STATURE

PATHOLOGIC

PROPORTIONATE

  • PRENATAL
  • Intrauterine growth retardation (IUGR)
    • Placental diseases
    • Infections
    • Teratogens
  • Dysmorphic syndromes
  • Chromosomal disorders
  • NORMAL VARIANTS
  • Familiar short stature
  • Constitutional growth delay
  • DISPROPORTIONATE
  • Skeletal dysplasia
  • Rickets
  • POSTNATAL
  • Malnutrition
  • Chronic diseases
    • Gastrointestinal
    • Cardiopulmonary
    • Infections
    • Renal
    • Hematologic
  • Drugs
  • Psychosocial dwarfism
  • Endocrine disorder
slide26

CLASSIFICATION OF SHORT STATURE

SHORT STATURE

PATHOLOGIC

PROPORTIONATE

  • PRENATAL
  • Intrauterine growth retardation (IUGR)
    • Placental diseases
    • Infections
    • Teratogens
  • Dysmorphic syndromes
  • Chromosomal disorders
  • NORMAL VARIANTS
  • Familiar short stature
  • Constitutional growth delay
  • DISPROPORTIONATE
  • Skeletal dysplasia
  • Rickets
  • POSTNATAL
  • Malnutrition
  • Chronic diseases
    • Gastrointestinal
    • Cardiopulmonary
    • Infections
    • Renal
    • Hematologic
  • Drugs
  • Psychosocial dwarfism
  • Endocrine disorder
slide31

CLASSIFICATION OF SHORT STATURE

SHORT STATURE

PATHOLOGIC

PROPORTIONATE

  • PRENATAL
  • Intrauterine growth retardation (IUGR)
    • Placental diseases
    • Infections
    • Teratogens
  • Dysmorphic syndromes
  • Chromosomal disorders
  • NORMAL VARIANTS
  • Familiar short stature
  • Constitutional growth delay
  • DISPROPORTIONATE
  • Skeletal dysplasia
  • Rickets
  • POSTNATAL
  • Malnutrition
  • Chronic diseases
    • Gastrointestinal
    • Cardiopulmonary
    • Infections
    • Renal
    • Hematologic
  • Drugs
  • Psychosocial dwarfism
  • Endocrine disorder
slide33

CLASSIFICATION OF SHORT STATURE

SHORT STATURE

PATHOLOGIC

PROPORTIONATE

  • PRENATAL
  • Intrauterine growth retardation (IUGR)
    • Placental diseases
    • Infections
    • Teratogens
  • Dysmorphic syndromes
  • Chromosomal disorders
  • NORMAL VARIANTS
  • Familiar short stature
  • Constitutional growth delay
  • DISPROPORTIONATE
  • Skeletal dysplasia
  • Rickets
  • POSTNATAL
  • Malnutrition
  • Chronic diseases
    • Gastrointestinal
    • Cardiopulmonary
    • Infections
    • Renal
    • Hematologic
  • Drugs
  • Psychosocial dwarfism
  • Endocrine disorder
slide34

CLASSIFICATION OF SHORT STATURE

SHORT STATURE

PATHOLOGIC

PROPORTIONATE

  • PRENATAL
  • Intrauterine growth retardation (IUGR)
    • Placental diseases
    • Infections
    • Teratogens
  • Dysmorphic syndromes
  • Chromosomal disorders
  • NORMAL VARIANTS
  • Familiar short stature
  • Constitutional growth delay
  • DISPROPORTIONATE
  • Skeletal dysplasia
  • Rickets
  • POSTNATAL
  • Malnutrition
  • Chronic diseases
    • Gastrointestinal
    • Cardiopulmonary
    • Infections
    • Renal
    • Hematologic
  • Drugs
  • Psychosocial dwarfism
  • Endocrine disorder
accepted indications for gh therapy
Accepted indications for GH therapy
  • Childhood GH deficiency
  • Growth failure associated with chronic renal insufficiency
  • Turner syndrome
  • IUGR
  • Adults with GH deficiency
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