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ENDOMETRIAL HYPERPLASIA INCIDENCE

ENDOMETRIAL HYPERPLASIA INCIDENCE. Arian Alikaj, Rubena Moisiu. Endometrial hyperplasia incidence.

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ENDOMETRIAL HYPERPLASIA INCIDENCE

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  1. ENDOMETRIAL HYPERPLASIA INCIDENCE Arian Alikaj, Rubena Moisiu

  2. Endometrial hyperplasia incidence Study PopulationPatients presented to hospital aged 18-60 years with the complaint: Menometrorrhagia.The study was conducted in SUOGJ "Koco Gliozheni"The study of 993 patients biopsy taken during the years 2003-2006.The average age of patients was 43 years (18-60)The total number of hyperplasia is 270 (27%)Diagnosis is supported by endometrial biopsy. Biopsy were examined by an experienced anatomopatologo

  3. Endometrial hyperplasia incidence • Table 1 Classification of endometrial hyperplasia (WHO,1994) • 1. Endometrial hyperplasia • a. Simple • b. Complex (adenomatous) • 2. Atypical endometrial hyperplasia • a. Simple • b. Complex (adenomatous with atypia)

  4. Endometrial hyperplasia incidence Simple hyperplasia Complex hyperplasia Atypical hyperplasia

  5. Endometrial hyperplasia incidence Is often associated: Polycystic ovary syndrome 54 (20%) Obesity 37 (13.%) Annovulation 77 (28.5%) Diabetes 22 (8.1%) Hormonal Therapy 5 (1.8%) Infertility 23 (8.5%) Tamoxifen use 18 (6.6%)

  6. Endometrial hyperplasia incidence Incidence of progression to invasive carcinoma in untreated endometrial hyperplasia Simple hyperplasia 1% Complex (adenomatous) hyperplasia <5% Simple hyperplasia with atypia 5-10% Complex (adenomatous) hyperplasia with atypia 25-30%

  7. Endometrial hyperplasia incidence

  8. Endometrial hyperplasia incidence Simple hyperplasia Complex hyperplasia Atypical hyperplasia

  9. Conclusions Endometrial hyperplasia incidence is higher among 50-60 years old women with peak age 54 years. The incidence of atypical hyperplasia increases significantly after age 60 years. Atypical hyperplasia is rare before age 30 years Obesity and polycystic ovary favor endometrial hyperplasia After age 30 years increases the frequency of endometrial hyperplasia with increasing probability every 5-years Among women aged 18-30 years the incidence of simple hyperplasia is 58/100000 woman / Years

  10. THANK YOU FOR YOUR ATTENTION

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