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GI Pathology II, Case 4. 60-year-old woman with easy fatiguability and hemoglobin of 10.2 g/100ml. Identify the structures. A Villous Adenoma B Tubular Adenoma. Tubular Adenomas. Polyp Stalk. Normal adjacent colon mucosa. Normal adjacent colon mucosa.

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gi pathology ii case 4
GI Pathology II, Case 4
  • 60-year-old woman with easy fatiguability and hemoglobin of 10.2 g/100ml.
slide3

A Villous Adenoma

B Tubular Adenoma

slide5

Tubular Adenomas

Polyp Stalk

Normal adjacent colon

mucosa

Normal adjacent colon

mucosa

Even on low power note the crowded, disorganized glands of the tubular adenoma

compared to the normal underlying colonic mucosa. The cells lining the glands of the polyp have hyperchromatic nuclei. There is no stalk invasion – the polyps are benign

slide7

Goblet

cells

Hyperchromatic

nuclei

The glands of the tubular adenoma are lined by goblet cells and epithelium

with elongated cells containing hyperchromatic nuclei

that are pseudostratified (atypical or “dysplastic” epithelium)

There is no invasion of the lamina propria or submucosa.

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