COGNITIVE SCIENCE 17 Drug Abuse or … Drug Abuse or… For Big Kids. Mike Datko, B.S. Features of drug abuse and addiction. Definition: how are abuse and addiction defined clinically? Positive reinforcement Negative reinforcement Opponent process theory Craving and relapse.
Mike Datko, B.S.
A state of drug dependence is defined similarly, with the additional requirement of the manifestation of physical withdrawal symptoms when drug use is stopped.
Koob (at UCSD) described addiction as involving “a cycle of spiraling dysregulation of brain reward systems that progressively increases, resulting in the compulsive use and loss of control over drug taking.”
Diagrams from Neurotopia.com
- Some routes, from fastest to slowest: