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Introduction. Hemochromatosis Alzheimer's Constant company A global, evolutionary Macarena I t’s not only good for X-Men DNA is history Somewhere in your genetic code is the tale of every plague, every predator, every parasite, and every planetary upheaval your ancestors mangled to survive.

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Introduction
Introduction

  • Hemochromatosis

  • Alzheimer's

  • Constant company

  • A global, evolutionary Macarena

  • It’s not only good for X-Men

  • DNA is history

    • Somewhere in your genetic code is the tale of every plague, every predator, every parasite, and every planetary upheaval your ancestors mangled to survive


Chapter 1
Chapter 1

  • Hemochromatosis is inherited—and the gene for it is very common in certain populations

  • Iron Locking- Vivkings- founder’s effect

  • Bubonic plague: 1/3 to ½= 25 million people

  • People with Hemochromatosis are less susceptible?

  • Increase in European populations every time the disease resurfaced over the ensuing three hundred years

  • Evolutionary bottleneck

  • We did ask for it!

  • Cystic fibrosis and TB


Chapter 3
Chapter 3

  • Sunlight: Vitamin D and Folic Acid

  • Skin Color

    • Dark to protect folate

    • Light to manufacture vitamin D

    • Inuit

  • High cholesterol to increase vitamin D

  • ACHOO

  • Alcohol flush response (alcohol vs. tea)

  • Slave trade and salt- evolutionary bottleneck

  • Environmentally dependent

  • What happens when the environment changes (moves or migrations?)


Chapter 4
Chapter 4

  • The fava bean- Where’s there folklore smoke, there’s medical fire

  • Free radicals and enzyme deficiency

  • Fava cultivation and favism

    • >400 million

  • Fruit, botanical birth control & poison

  • JBS Haldane

    • SCD

    • Favism

    • Malaria

  • Why cultivate what can kill you?


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