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dynGraph. “Don't stop for nobody This time I'll keep my feet on solid ground Now I understand myself when I'm down ”. Interactive visualization of 'factorial planes' integrating numerical indicators…and the beat goes on. Example. PPAR-alpha mice (P. Martin) Individuals: 40 mice

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Dyngraph

dynGraph

“Don't stop for nobodyThis time I'll keep my feet on solid groundNow I understand myself when I'm down”

Interactive visualization of 'factorial planes' integrating numerical indicators…and the beat goes on


Example

Example

  • PPAR-alpha mice (P. Martin)

  • Individuals: 40 mice

    • 20 wild, 20 PPAR-alpha deficient

    • 5 diets (dha, efad, lin, ref, tsol)

  • Variables:

    • 120 genes

    • 21 hepatic fatty acids

  • Objective: to highlight similarities between genes expression and clinical variables


Example1

Example

  • The 5 diets

    • Dha: DHA is the most abundant essential fatty acid (polyunsaturated fatty acids) in the brain and retina, omega 3 fatty acids

    • Efad: Essential Fatty Acid Deficient, only saturated fatty acids based on hydrogenated coconut oil

    • Lin: flax oil, omega 3 fatty acids

    • Ref: according to the advised nutritional supplies for the French population, 6 omega 6 for 1 omega 3

    • Tsol: sunflower oil, essentially omega 6


Example2

Example

  • The peroxisome proliferator-activated receptors (PPARs) are a group of proteins that function as transcription factors regulating the expression of genes.

  • PPARs play essential roles in the regulation of cellular differentiation, development, and metabolism (carbohydrate, lipid, and protein) of higher organisms.


Main features data frame factorial planes

Main features: data frame & factorial planes

  • Change the axes

  • Qualitative and quantitative values-representation

  • Categories and quantitative variables visual description

  • Labels edition (move and delete)

  • Points edition (delete)

  • Export to png, pdf, svg and emf


Main features factorial planes

Main features: factorial planes

  • Axes visual description

  • Quality of representation visual index

  • Move quickly from one plane to another

  • PCA, CA, MCA, MFA, AFDM


Data flow

Data flow

rJava

FactoMineR

raw data


Thanks for your attention

Thanks for your attention

And the beat goes on…


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