Treatment of Keratoconus Using Riboflavin-Induced Corneal Collagen Crosslinking. Authors: Anne Keating, M.D. 1,2 , Kathryn Colby, M.D., Ph.D. 2 , Roberto Pineda, M.D. 2 , Michael Endl, M.D. 4 , Thomas Elmer, M.D. 4 , Sandra Everett, M.D. 1 and James Reidy, M.D. 1
Authors: Anne Keating, M.D.1,2, Kathryn Colby, M.D., Ph.D.2, Roberto Pineda, M.D.2, Michael Endl, M.D.4, Thomas Elmer, M.D.4, Sandra Everett, M.D.1 and James Reidy, M.D.1
1SUNY Buffalo, 2Massachusetts Eye and Ear Infirmary, 3Fichte Endl Elmer Eyecare, Buffalo, NY
Financial Disclosure: The authors of this poster have no financial interest in the subject matter of this poster.
The Caporossi-Baiocchi-Mazzotta (CBM) VEGA X-linker was developed by Aldo Caporossi, Cosimo Mazzotta, and Stefano Baiocchi in collaboratioin with the Italian firm C.S.O. The CBM X-linker is a device that emits ultraviolet (UV) radiation at 370 nm (peak absorption of riboflavin) (figure 1).
The device is designed to produce a timely, homogeneous dose of irradiation and deliver it to a 9 mm diameter spot size at a distance of between 1.5 and 1.8 cm. This working distance allows for more efficient focusing on the cornea. A small digital video camera is included in the center of the UV-A array in order to monitor the aiming-beam alignment and to control the centration of the irradiated area. The picture from the video camera is shown on an LCD (liquid crystal display) monitor mounted on the control unit of the equipment (figure 2).
Best Corrected Visual Acuity
The treatment of keratoconus using UVA induced riboflavin corneal collagen cross linking has been conducted in Germany and Italy over the past decade with fairly consistent and positive results. The table below summarizes the follow-up and results.