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Spirometry reference values: a systematic review

Spirometry reference values: a systematic review. Turma 1 Docente: Dr. Tiago António Queirós Jacinto Regente: Prof. Dr. Altamiro Pereira. INTRODUCTION TO MEDICINE 2009/2010. Problem/Research Question. ARE THE SPIROMETRY REFERENCE VALUES USED IN PORTUGAL ADEQUATE?

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Spirometry reference values: a systematic review

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  1. Spirometry reference values: a systematic review Turma 1 Docente: Dr. Tiago António Queirós Jacinto Regente: Prof. Dr. Altamiro Pereira INTRODUCTION TO MEDICINE 2009/2010

  2. Problem/Research Question ARE THE SPIROMETRY REFERENCE VALUES USED IN PORTUGAL ADEQUATE? Have the values changed in the last ten years? Were the reference values obtained correctly?

  3. Introduction Reference values are important statistical values to obtain medical relevant information; They vary with the age, gender, and other characteristics determining whether he/she is healthy or not; It is crucial to have adequate, current and correct reference values when performing an exam, in order to avoid misdiagnoses.

  4. Spirometry is one of the most important medical exams to assess the function of a person’s pulmonary capacity.  This test consists in measuring the volume of air and flow that has been exhaled into a spirometer.

  5. Forced Vital Capacity or FVC Forced Expiratory Value during the first second or FEV1 Two reference values are commonly used: Both values are standardized (reference values for healthy lung function) allowing the detection of pulmonary problems by comparison with the obtained values.

  6. Variability of the different sets of reference values Strong influence over the diagnostics Likely hypothesis: inadequate reference values are being applied in the Portuguese population SYSTEMATIC REVIEW

  7. Summarize the wide range of data that has been published in the last decade; • Analyze and rate the obtained information using the STROBE checklist; • Select a new set of up to date reference values and suggest its use in Portugal. Aims

  8. Methods

  9. Study design: systematic review;   • Data Sources (online databases): • Key words: Methods SPIROMETRY Reference values FEV FVC

  10. Inclusion Criteria Exclusion Criteria • Articles written in Portuguese or English; • Articles referring to studies performed in humans; • Articles which refer the equipment used; • Published from 1998 to 2008. • Articles whose full text can not be achieved for free • Values referring to diseased individuals • Articles about studies with insufficient or inconclusive data. Criteria

  11. Start Search Read Title And Abstract Is It written in Portuguese or English? No Yes Exclude Select and Save for further analysis Research Method Remove Repeated Articles Remove all not related articles

  12. Select and Save for further analysis Read Abstract Apply Inclusion/Exclusion Criteria Read By A Third Reviewer Who Decides To Include Or Not Both Do Not Agree Read Full Text By Two Reviewers Both Decide To Exclude Exclude Both Decide To Include Include

  13. Conclude that some reference values are outdated and inadequate; • Realize that inaccurate reference values lead to a wrong diagnosis of pulmonary diseases; •   Reunite a list of adequate spirometry reference values to our country. • Improve the accuracy and reliability of pulmonary diseases diagnosis Expectedresults

  14. Turma 1 2009/2010

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