THE RED CELL MEMBRANE. BLOOD BANKING Prepared by: JOSEPHINE C. MILAN, RMT, MSMT DEPARTMENT OF MEDICAL LABORATORY TECHNOLOGY UNIVERSITY OF TABUK. OBJECTIVE and FOCUS.
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JOSEPHINE C. MILAN, RMT, MSMT
DEPARTMENT OF MEDICAL LABORATORY TECHNOLOGY
UNIVERSITY OF TABUK
Main function of red cells:
Importantfor RBC survival and function:
1. normal chemical composition and structure of the RBC membrane
2. hemoglobin structure and function
3. RBC metabolism
Proteins: form a meshwork that traverse the lipid bilayer, calledmembrane skeleton
cholesterol = 40 %;
glycolipids = 10 %
hydrophobic (nonpolar) tails towards inside of cell
hydrophilic (polar) head groups towards outside (extracellular) or the inside (cytoplasmic ) surface
Ex: (band 3 and GPA) like Kell and Kx, Rh and RhAG