CLINICAL PATHOLOGY. Clinical Textbook for Veterinary Technicians by Dennis M. Mccurnin 4 th edition Saunders. Accurate clinical pathology data is invaluable in the diagnosis of diseases in all species.
Clinical Textbook for Veterinary Technicians by Dennis M. Mccurnin 4th edition Saunders
Accurate clinical pathology data is invaluable in the diagnosis of diseases in all species.
Repetition of the data (tests) provides a means of monitoring and evaluating the success of chosen treatments.
The most commonly used clinical laboratory procedures in veterinary practices are
Hem(e) = blood
Ology = study of
Hematology = study of blood
CBC = complete blood count
Provides the veterinarian with the following information
* PCV (packed cell volume)
* WBC count (leukocytes)
* RBC count (erythrocytes)
* RBC indices
* total plasma protein
* evaluation of the blood smear for RBC morphology and WBC differential
Hematological procedures are performed on anticoagulated whole blood.
The preferred anticoagulant is EDTA and is commercially available in “purple top” tubes.
microhematocritcentrifuge (to determine PCV)
refractometer (determine the plasma protein and urine specific gravity)
hemacytometer (counting chamber)
PCV = percentage of total blood volume accounted for by RBCs
RBC indicies = calculations provided when automated analyzers are used.
MCV = mean corpuscular volume
MCH = mean corpuscular hemoglobin
MCHC = mean corpuscular hemoglobin concentration
* Could be used to help evaluate and determine causes of anemia.
The erythrocytes of most mammals are disc shaped and anuclear.
They appear flat with an area in the center of the cell with less hemoglobin.
The RBCs of animals differ in size.
From largest to smallest: dog
* Anisocytosis = RBCs that vary in size (cows more than other species)
* Rouleaux – groupings of RBCs that resemble stacked coins (it is important to establish this from true agglutination)
Possible Parasites in RBCs:
* Haemobartonellafelis – the parasite responsible for the feline infectious anemia.