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弥散性血管内凝血 Disseminated Intravascular Coagulation PowerPoint PPT Presentation


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弥散性血管内凝血 Disseminated Intravascular Coagulation. 长春中医药大学病理教研室 于兰英. 凝血 系统. 纤溶 系统. 抗凝 系统. 在某些致病因素作用下,机体凝血系统被激活,大量可溶性促凝物质入血,而引起的以凝血功能障碍为主要特征的病理过程。. 高凝状态. 消耗性低凝状态. 纤溶系统亢进. 出血 休克 器官功能障碍 溶血性贫血. 病因. 凝血因子和血小板激活. 促凝物质入血、凝血酶↑. 凝血功能 失常. 微循环内广泛微血栓形成. 凝血因子、血小板消耗,继发纤溶. 属于一种严重的血液系统紊乱综合征,

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弥散性血管内凝血 Disseminated Intravascular Coagulation

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Disseminated intravascular coagulation

Disseminated Intravascular Coagulation


Disseminated intravascular coagulation


Disseminated intravascular coagulation


Disseminated intravascular coagulation


Disseminated intravascular coagulation


Disseminated intravascular coagulation

a- Ca 2+-

Ca 2+

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Ca 2+

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Disseminated intravascular coagulation

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Disseminated intravascular coagulation

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Disseminated intravascular coagulation

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Disseminated intravascular coagulation

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C ( PC )

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Disseminated intravascular coagulation

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TFPIa

TFPI/aa/TF

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Disseminated intravascular coagulation

(Haparin)

(1)a

(2)

ATIII

APC

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Disseminated intravascular coagulation

  • (PA)

  • (PAI)


Disseminated intravascular coagulation

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uPA

tPA

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PAI-1

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FDP


Disseminated intravascular coagulation

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DIC


Disseminated intravascular coagulation

Microthrombus

(myocardium)

Microthrombus

(liver)


Disseminated intravascular coagulation

DIC

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Disseminated intravascular coagulation

(+)

-

TF


Disseminated intravascular coagulation

TF-Ca2+-VII

(+)

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Disseminated intravascular coagulation

ADP

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Disseminated intravascular coagulation

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(+)


Disseminated intravascular coagulation

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Disseminated intravascular coagulation

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DIC


Disseminated intravascular coagulation

DIC

Shwartzman

24h

DIC


Disseminated intravascular coagulation

TF

(+)

DIC


Disseminated intravascular coagulation

pH

DIC

PAI


Disseminated intravascular coagulation

DIC

RBC


Disseminated intravascular coagulation

DIC

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Disseminated intravascular coagulation

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Disseminated intravascular coagulation

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Disseminated intravascular coagulation

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Disseminated intravascular coagulation

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Disseminated intravascular coagulation

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Disseminated intravascular coagulation

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Disseminated intravascular coagulation

C3aC5a

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Disseminated intravascular coagulation

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Disseminated intravascular coagulation

DIC

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2.RBC

3.


Disseminated intravascular coagulation


Disseminated intravascular coagulation

5

  • DIC


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