1 / 2

lnsulin Receptor Pathway

INSULIN. Fyn. Nck. SHC. GRB2. GLUT4. SOS. IRS1. Flotillin. Crk. Ras. GTP. CAP. Rab4. PI3K. GRB10. APS. GLUT4 Vesicle. Raf. IRS1/2. SHC. PPtase1. c-CbI. MEKs. Akt PKB. Rac. Insulin. JNK. PDK. PKC. mTOR. Insulin. P. P. P. P. P. P. P. P. P. P. P. P. P. P.

tola
Download Presentation

lnsulin Receptor Pathway

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. INSULIN Fyn Nck SHC GRB2 GLUT4 SOS IRS1 Flotillin Crk Ras GTP CAP Rab4 PI3K GRB10 APS GLUT4Vesicle Raf IRS1/2 SHC PPtase1 c-CbI MEKs AktPKB Rac Insulin JNK PDK PKC mTOR Insulin P P P P P P P P P P P P P P P P P P P ERKs GlycogenSynthase BAD EAI EAI GSK3 p70S6K eIF4EBP FKHRL1 EEF2K c-Jun BAD 14-3-3 eIF2B c-Fos EEF2 eIF4 S6 Elk c-CbI Glucose PIP2 PIP3 Lipid Raft InsulinReceptor GLUT4Translocation lnsulin Receptor Pathway PIP2 PIP3 ReceptorInternalization H+ Insulin Degradation& ReceptorDephosphorylation H+ ATP Citrate lyase EBS Translation Translation Anti-apoptosis Fatty AcidSynthesis GeneExpression TRE Gene Expression

  2. INSULIN Fyn Nck SHC GRB2 GLUT4 IRS1 Flotillin Crk CAP Rab4 PI3K APS GLUT4Vesicle IRS1/2 SHC c-CbI Rac Insulin JNK PKC Insulin P P P P P P P P P P P P P P P P P GlycogenSynthase EAI EAI c-Jun c-Fos c-CbI Glucose Lipid Raft PIP2 PIP3 InsulinReceptor Cell membrane GLUT4Translocation lnsulin Receptor Pathway.A SIMPLIFIED VERSION PIP2 PIP3 ReceptorInternalization H+ Insulin Degradation& ReceptorDephosphorylation H+ Nucleus Fatty AcidSynthesis Translation Gene Expression Anti-apoptosis Translation GeneExpression TRE

More Related