1 / 20

Free Classroom Resources from HHMI for Teaching Evolution, Part 2

Free Classroom Resources from HHMI for Teaching Evolution, Part 2. Megan Stine stinem@hhmi.org June 19, 2014. Evolution: Behind the Scenes. Evolving Switches, Evolving Bodies. Film guides Virtual lab Classroom activities: Using Genetic Crosses to Analyze a Stickleback Trait

tirzah
Download Presentation

Free Classroom Resources from HHMI for Teaching Evolution, Part 2

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Free Classroom Resources from HHMI for Teaching Evolution, Part 2 Megan Stine stinem@hhmi.org June 19, 2014

  2. Evolution: Behind the Scenes

  3. Evolving Switches, Evolving Bodies • Film guides • Virtual lab • Classroom activities: • Using Genetic Crosses to Analyze a Stickleback Trait • Modeling the Regulatory Switches of the Pitx1 Gene in Stickleback Fish

  4. Evolving Switches, Evolving Bodies Film • http://www.hhmi.org/biointeractive/making-fittest-evolving-switches-evolving-bodies

  5. Which phenotype is dominant? • Assumption: single-gene trait, 2 alleles, normal dominance • Cross between a marine stickleback and one from Bear Paw Lake • Parents are homozygous • F is dominant, f is recessive

  6. Predict the results of the crosses 1st generation 2nd generation Ff Ff Ff FF Ff Ff Ff ff Pelvic spines present:absent = Pelvic spines present:absent = 1:0 3:1 1:3 0:1

  7. Sorting by Phenotype With pelvic spines Without pelvic spines

  8. Do the data support your hypothesis? • Sort the F1 cards: • Fish with pelvic spines • Fish without pelvic spines • Sort the F2 cards • Ratio of fish with:without pelvic spines in F1? • Ratio of fish with:without pelvic spines in F2? 1:0 3.4:1 Was our initial assumption correct? Is this a single-gene trait? Was your hypothesis correct? Which phenotype is dominant?

  9. Virtual Lab

  10. Natural Selection in Humans • Film guides • Classroom resources: • Nature of Science • Mendelian Genetics, Pedigrees, and Chi-square Analysis • How Fibers Form • Population Genetics

  11. Natural Selection in Humans Film • http://www.hhmi.org/biointeractive/making-fittest-natural-selection-humans

  12. Mendelian Genetics Activity • Punnett squares • Pedigree analysis • Pedigree creation • Chi-square analysis • Data prediction • Important notes: • A is normal allele • S is sickle cell allele • AA has normal RBC phenotype • AS has sickle cell trait • SS has sickle cell disease

  13. Question #1: Intro Punnett • Chance of normal RBC in high and low oxygen? • Chance of SCD? • Chance of 3 children with SCD? • Chance of 2 children with sickle cell trait and 1 with SCD? • Child without SCD, what chance he/she has trait? 1/4 1/4 1/64 1/16 2/3 AS AA AS SS

  14. Question #6: Intro Pedigree • Genotype of: • 1st gen male? • 2nd gen daughter? • Individual #3? • If family moves to lowlands of E. Africa, 4/5 males will have two genetic advantages. What are they? AS SS AS

  15. Human Evolution Click & Learn

  16. Teacher Guides

  17. Holiday Lecture Series

  18. BioInteractive.org

  19. Coming in Fall 2014…

  20. Thank you for your time and attention! stinem@hhmi.org Sign up for our newsletter at biointeractive.org Like us on Facebook!

More Related