Mortemus mort ality in e pilepsy m onitoring u nit s tud y
This presentation is the property of its rightful owner.
Sponsored Links
1 / 7

MORTEMUS MORT ality in E pilepsy M onitoring U nit S tud y PowerPoint PPT Presentation


  • 175 Views
  • Uploaded on
  • Presentation posted in: General

MORTEMUS MORT ality in E pilepsy M onitoring U nit S tud y. USING IN-HOSPITAL PRE-SURGICAL MONITORING DATA TO ASSESS RISKS, MECHANISMS AND RISK FACTORS OF SUDDEN UNEXPECTED DEATH IN EPILEPSY (SUDEP) Proposal for an ILAE sponsored European study Philippe Ryvlin, Lyon

Download Presentation

MORTEMUS MORT ality in E pilepsy M onitoring U nit S tud y

An Image/Link below is provided (as is) to download presentation

Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.


- - - - - - - - - - - - - - - - - - - - - - - - - - E N D - - - - - - - - - - - - - - - - - - - - - - - - - -

Presentation Transcript


Mortemus mort ality in e pilepsy m onitoring u nit s tud y

MORTEMUSMORTality in Epilepsy Monitoring Unit Study

USING IN-HOSPITAL PRE-SURGICAL MONITORING DATA TO ASSESS RISKS, MECHANISMS AND RISK FACTORS OF SUDDEN UNEXPECTED DEATH IN EPILEPSY (SUDEP)

Proposal for an ILAE sponsored European study

Philippe Ryvlin, Lyon

Torbjörn Tomson, Stockholm


Why epilepsy surgery patients

Why Epilepsy Surgery Patients?

  • Population with highest risk

  • Population/situation with most and best data


Why collaboration

Why collaboration?

  • Because SUDEP is a rare event

  • Broad collaboration is the only way to collect sufficient numbers


Mortemus objectives

MORTEMUS Objectives

  • To quantify the risk of death, SUDEP, and “near SUDEP”, in patients with drug resistant partial epilepsy who have undergone long-term video-EEG monitoring

  • To gather up to 20 cases of SUDEP / “near SUDEP” for whom concomitant video, EEG and EKG data will be available

  • To provide evidence regarding the respective role of cardiac vs. respiratory dysfunctions in the pathophysiology of SUDEP

  • To identify risk factors for SUDEP in patients with refractory epilepsy


Objectives continued

Objectives continued

  • To evaluate the feasibility and rationale for launching a large scale European prospective study that aims to confirm the above retrospective data, and also to determine whether heart rate variability parameters can predict the risk of SUDEP


Mortemus methods

MORTEMUS Methods

  • To establish a network of collaborating epilepsy surgery centres in Europe, aiming at in total 3-4000 patient years of monitoring during the past 10 years

  • Distribution of questionnaire regarding SUDEP or near-SUDEP cases during monitoring in these units

  • Centralised analysis of all data (EEG, ECG, video etc) from SUDEP/near-SUDEP cases for a descriptive study

  • Case-control study of SUDEP/near-SUDEP cases vs. Non-SUDEP epilepsy controls from the same monitoring unit


Sudep under monitoring cerebral electrical shutdown

SUDEP under Monitoring”Cerebral Electrical Shutdown”


  • Login