US-Africa Materials Institute (USAMI) Winston O. Soboyejo, Princeton University, DMR 0231418

1. US-Africa Materials Institute (USAMI)Winston O. Soboyejo, Princeton University, DMR 0231418 Coated AFM tips used to measure strong adhesive interactions between leutinizing hormone releasing hormone-(LHRH) and LHRH receptors on breast cancer cells Modeled nanoparticle cluster entry into cancer cells using thermodynamics and kinetics concepts (predicted maximum cluster size consistent with experiments) Developed a multi-modal device that can kill cancer cells by hyperthermia and the local delivery of chemotherapy drugs to cancer tissue Studied the controlled killing of cancer cells using localized drug delivery and hyperthermia Modeled the effects of the localized delivery of drugs and temperature diffusion on the killing of breast cancer cells nN USAMI Multi-modal device AFM Adhesion Force Measurements (b) Predicted Temperature Distribution Due to Hyperthermia Potential Application Of Implantable Device

2. USAMI-IRC Summer Science Outreach Program Winston O. Soboyejo, Princeton University, DMR 0231418 USAMI partnered with the International Rescue Committee to offer a science outreach program for about newly-arrived refugee youth Through this 6-week summer program, Junior High and High School-aged children who once lived in refugee camps learned about science of water filtration and alternative energy by designing clay water filters and solar energy cookers USAMI-supported undergraduate and graduate students also acted as mentors, giving insights into the American higher education process and application procedures The 50 refugee students hailed from Sierra Leone, Liberia, Guinea, Burma, Nepal, Tibet and Iraq Students engaged in campus tours and labs The students also had the opportunity to visit Princeton University, where they were treated to lab and campus tours and had the chance to talk with Princeton students who were once refugees themselves