International Symposium „Inflammation, Degeneration and Regeneration - from Basic Mechanisms

1. Magdeburger Forschungsverbund„Neurowissenschaften“&„Immunologie und Molekulare Medizin der Entzündung“ Hundertwasserhaus International Symposium „Inflammation, Degeneration and Regeneration - from Basic Mechanisms to Clinical Manifestations“ 30.11. - 01.12. 2006 Magdeburg Hotel „Ratswaage“ 39104 Magdeburg, Ratswaageplatz 1- 4 Magdeburger Forschungsverbund Medizinische Fakultät Otto-von-Guericke-Universität Magdeburg International Symposium30.11. to 01.12.2006 Hotel "Ratswaage“: circle in center of map, close to Magdeburg DB-Main station. By foot via "Ernst Reuter Allee" and Pedestrian area in "Breiter Weg“. Hotel RatswaageRatswaageplatz 1-439104 Magdeburg Telefon: 0391 59 26 0 0391 59 26-111Fax: 5926 115 und 56 19 615Internet: www.ratswaage.de Web-page: http://www.med.uni-magdeburg.de/fme/rf/mfv

2. Magdeburger Forschungsverbund„Neurowissenschaften“&„Immunologie und Molekulare Medizin der Entzündung“ Magdeburger Forschungsverbund„Neurowissenschaften“&„Immunologie und Molekulare Medizin der Entzündung“ Thursday, 30.11.2006 16.00 Registration at Reception desk Hotel „Ratswaage“ 16.00 to 16.30 Mounting of posters 16.30 Welcome addresses Ministry for Cultural Affairs Rector Otto-von-Guericke-University Magdeburg Dean Medical Faculty Speaker of Magdeburger Forschungsverbund Opening of Symposium 16.45 to 18.45Scientific session Session 1: Inflammation, immunology and neurosciences at crossroads: From molecules to diseases Chairs: B. Bonnekoh, G. Reiser, G. Wolf 16.45 to 17.15 K. Aktories (Freiburg) „Novel insights into structure and functions of Rho-modifying clostridial cytotoxins“ 17.15 to 17.45 J. Schröder (Kiel) „Defense mechanisms of human skin and mucous membrane“ 17.45 to 18.15 G. G. Haddad (San Diego, USA) „Hypoxic neuronal injury: Insights from vertebrate and invertebrate models“ 18.15 to 18.45 N. Vergnolle (Calgary, Canada) Protease Signalling: cross roads between inflammation and pain“ Lectures: time includes 5 min discussion 19.00 to 21.00 Welcome Reception with „Poster-Party“ Snacks, Drinks & Poster discussion Posters are displayed until Friday afternoon Organizers: A. Roessner (dean), G. Reiser (speaker), B. Bogerts, B. Bonnekoh, V. Höllt, W. König, P. Malfertheiner, M. Naumann, B. Schraven, O. Ullrich, C.-W. Wallesch, P. Wieacker, G. Wolf Internet: http://www.med.uni-magdeburg.de/fme/rf/mfv/

3. Magdeburger Forschungsverbund„Neurowissenschaften“&„Immunologie und Molekulare Medizin der Entzündung“ Magdeburger Forschungsverbund„Neurowissenschaften“&„Immunologie und Molekulare Medizin der Entzündung“ Friday, 01.12.2006 12.00 to 13.00 Lunch 13.00 to 14.00 Afternoon session Session 3: General aspects of immunology Chairs: W. König, P. Malfertheiner 13.00 to 13.30 R. Pabst (Hannover) „ Is the „common mucosal immune system“ really common? Comparison of structure and immune functions in intestine and lung in different species“ 13.30 to 14.00 I. Bechmann (Frankfurt) „What is immune privilege (not) ?“ lectures: time includes 5 min discussion 14.00 to 14.30 Coffee break 14.30 to 16.00 Guided poster tour - Section 2 Chairs: M. Röllinghoff,B. Bonnekoh 15.45 to 16.00 Poster dismounting Friday, 01.12.2006 16.00 to 18.30 Evening sessions Session 4: Neurodegenerative diseases and immunology Chairs: B. Bogerts, V. Höllt 16.00 to 16.30 I. Klyubin (Dublin, Ireland) „Alzheimer´s disease disrupted synaptic plasticity by amyloid ß-protein“ 16.30 to 17.00 M. Rothermundt (Münster) „Immune pathology in schizophrenia: The role of glial cells“ 17.00 to 17.30 B. Sperner-Unterweger (Innsbruck, Austria) „Depression and immunology“ Session 5: Neurodegeneration and Neuroregeneration Chairs: V. Höllt, O. Ullrich 17.30 to 18.00 A. Storch (Dresden) „Mesencephalic neural stem cells in regenerative approaches in Parkinson´s Disease“ 18.00 to 18.30 J. Schulz (Göttingen) „Mechanisms of neuronal death and inflammation in models of Parkinson´s Disease“ lectures: time includes 5 min discussion 18.30 End of symposium and concluding remarks 19.30 Reception for invited speakers by Dean and Faculty

4. Magdeburger Forschungsverbund„Neurowissenschaften“&„Immunologie und Molekulare Medizin der Entzündung“ Magdeburger Forschungsverbund„Neurowissenschaften“&„Immunologie und Molekulare Medizin der Entzündung“ Saturday, 02.12.2006 Possible excursions and sightseeing for visitors: 29th Exhibition of the Council of Europe „Holy Roman Empire of German Nation 962 - 1806“ (Heiliges Römisches Reich Deutscher Nation 962 - 1806) in „Kulturhistorisches Museum Magdeburg“, open 10.00 to 19.00 (http://www.dhm.de/ausstellungen/heiliges-roemisches-reich/) Waterway crossing („Wasserstraßenkreuz“) - the greatest through bridge (Trogbrücke“) in Europe, carrying a canal over the river Elbe and a historic ship´s lift („Schiffshebewerk“) (www.magdeburg-tourist.de) Tour of historic town (cathedral, monastery,etc.) Friday, 01.12.2006 8.30 to 10.30Morning session Session 2: Disease processes and model systems Chairs: M. Naumann, B. Schraven 8.30 to 9.00 M.L. Schmitz (Giessen) „Mechanisms of the DNA-damage induced p53 response“ 9.00 to 9.30 B. Kenny (Newcastle, UK) „Enteropathogenic E. coli inhibition of antimicrobial and inflammatory responses in a small intestinal model system“ 9.30 to 10.00 T. Pap (Münster) „Modulation of fibroblast activation in destructive inflammatory arthritis - getting from bench to beside“ 10.00 to 10.30 L. Minghetti (Rom, Italy) „Microglial activation as a model for brain inflammation“ Lectures: time includes 5 min discussion 10.30 to 12.00 Guided poster tour - Section 1 Chairs: H. K. Müller-Hermelink, C.-W. Wallesch and coffee International Symposium is organised by „Magdeburger Forschungsverbund“ Speaker: Prof. Dr. Georg Reiser, Otto-von-Guericke-Universität Magdeburg, Medizinische Fakultät, Institut für Neurobiochemie, Leipziger Str. 44, 39120 Magdeburg, E-Mail: georg.reiser@medizin.uni-magdeburg.de Funding: Bundesministerium für Bildung und Forschung Förderinitiative NBL3 - FKZ 01ZZ0407