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Laboratory of SYSTEMS BIOLOGY PowerPoint PPT Presentation


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Trout. Rat. Laboratory of SYSTEMS BIOLOGY. Comparative experimental and computational studies on cardiac myocytes. Animal Models: Rat, trout, wild type and transgenic mouse. Bioenergetics Influence of intracellular compartmentation and diffusion restrictions on bioenergetics

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Laboratory of SYSTEMS BIOLOGY

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Laboratory of systems biology

Trout

Rat

Laboratory of SYSTEMS BIOLOGY

Comparative experimental and computational studies on cardiac myocytes

Animal Models: Rat, trout, wild type and transgenic mouse

Bioenergetics

Influence of intracellular compartmentation and diffusion restrictions on bioenergetics

Mechano-Energetics

Interaction between mechanics and energetics of the heart

Electrophysiology

Measurements of intracellular ion concentrations

Calcium Signaling

Examination of the causes of unstable calcium regulation

Scientific Computing

Open source scientific software tools: Image enhancement, data acquisition and analysis

Cardiac Myocytes


Laboratory of systems biology

Laboratory of SYSTEMS BIOLOGY

Cell membrane (green), F-Actin (red)

Active Collaborations:

Shey-Shing Sheu, University of Rochester, USA

Craig A. Lygate, Oxford University, UK

Eric A. Sobie, Mount Sinai School of Medicine, USA

Funding Agencies:

Wellcome Trust (UK)

Estonian Ministry of Education and Research

Estonian Science Foundation


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