Asthma. Most common chronic illness of childhood, affecting approximately 10% children. Available preventive therapies for persistent asthma include inhaled delivery system containing corticosteroids and long acting beta agonists. Adherence with inhaled therapies is poor in pediatrics.
Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.
delivery system containing corticosteroids and long acting beta agonists.
These are solid dosage forms that dissolve or disintegrate within a
Minute in the oral cavity without the need of water or chewing and have a pleasant taste.
UV Spectrophotometric method for analysis of Montelukast Sodium
Detection lmax 342 nm
Linearity range 10-50 mg/ml
Slope ± SD 0.0194 ± 0.0014
Regression coefficient 0.999
The tablet weight was fixed to 150 mg.
Montelukast Sodium Active
Avicel PH102 Diluent
Indion 414 Superdisintegrant
Instacoat Strawberry flavor Flavor
Supplied by Ideal Cures Pvt Ltd.
Magnesium stearate Anti adherent
Appearance Flat beveled tablets off white in color
Dimensions 9 mm in diameter
Weight variation (mg) ± SD 150 ± 2.87
Hardness (kg/cm2) 3-4
In-vitro disintegration time (sec) 20
Drug content (%) 101.2% ± 1.34
Drug release (%)
Apparatus – USP Type II
Medium – 500 ml Water 95%
rpm – 100, Time – 30 min
The authors thank