Asthma. Most common chronic illness of childhood, affecting approximately 10% children. Available preventive therapies for persistent asthma include inhaled delivery system containing corticosteroids and long acting beta agonists. Adherence with inhaled therapies is poor in pediatrics.
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delivery system containing corticosteroids and long acting beta agonists.
These are solid dosage forms that dissolve or disintegrate within a
Minute in the oral cavity without the need of water or chewing and have a pleasant taste.
UV Spectrophotometric method for analysis of Montelukast Sodium
Detection lmax342 nm
Linearity range10-50 mg/ml
Slope ± SD0.0194 ± 0.0014
The tablet weight was fixed to 150 mg.
Instacoat Strawberry flavorFlavor
Supplied by Ideal Cures Pvt Ltd.
Magnesium stearateAnti adherent
AppearanceFlat beveled tablets off white in color
Dimensions9 mm in diameter
Weight variation (mg) ± SD150 ± 2.87
In-vitro disintegration time (sec)20
Drug content (%)101.2% ± 1.34
Drug release (%)
Apparatus – USP Type II
Medium – 500 ml Water95%
rpm – 100, Time – 30 min
The authors thank