Hypercoagulable States. Hypercoagulable States. Acquired versus inherited “Provoked” vs idiopathic VTE Who should be tested for inherited thrombophilia ? What tests should be done & when? Anticoagulation recommendations Should family members be tested?. Virchow’s triad.
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-Protein C, protein S, AT III (functional)
Asherson et al., Lupus, 2003, 12:530
-Unusually severe thrombosis
-Recurrent thrombosis in setting of adequate anticoagulation
-Inability to adequately anticoagulate