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بسم الله الرحمن الرحيم

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بسم الله الرحمن الرحيم. Developmental & Genetic Diseases By Dr. Ghada Ahmed Lecturer of pathology Benha Faculty of Medicine. Developmental disorders. Definition Teratogenic factors: Ch emicals & drugs I onizing radiation I nfection to mother Ch romosomal/ genetic abnormalities.

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بسم الله الرحمن الرحيم

Developmental & Genetic Diseases

By

Dr. Ghada Ahmed

Lecturer of pathology

Benha Faculty of Medicine

developmental disorders
Developmental disorders
  • Definition
  • Teratogenic factors:

Chemicals & drugs

Ionizing radiation

Infection to mother

Chromosomal/ genetic abnormalities

effect of teratogenecity
Effect of Teratogenecity
  • Severe
  • Less severe
  • Later on life
genetic facts
Genetic facts

46, XX

46, XY

gene mutation
Gene mutation

Permanentchange in DNA sequence of certain gene

Abnormal gene

New properties

gene mutation1
Gene mutation
  • Point mutation
slide21

Polygenetic diseases

  • Multi-factorial diseases
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