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????????????????????,?????????????????,????????????? ? ??Max Delbruck. ??????(cell theory):. T. Schwan ( ???? ) ? M. Schleiden ( ???? )???????(1839-1840) (?) ??????????????(unit of structure)(?) ??????????????(unit of physiology)(?) ???????????;? ?All arise from pre-ex

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A tour of the cell

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A tour of the cell

(A tour of the cell)

2003.09.18


A tour of the cell

Max Delbruck


Cell theory

cell theory

T. Schwan ( ) M. Schleiden ( )(1839-1840)

() (unit of structure)

() (unit of physiology)

() All arise from pre-existing cells.


Cell size

( cell size )

mycoplasma ( 0.1~0.2um ) ( prokaryotes ) ( 1~10um ) ( eukaryotic cells) ( 10~100um ) (Fig.7.1)


How to study cells

(How to study cells)

().

1. ( light microscope )

2. ( electron microscope EM )

a. ( transmission electron microscope TEM )

b. ( scanning electron microscope SEM )


How to study cells1

(How to study cells)

()

( organelles )

(cell fractionation) (Fig.7.3)


Prokaryotic cells eukaryotic cells fig 7 4 fig 7 7 fig 7 8

( prokaryotic cells )( eukaryotic cells )(Fig.7.4,Fig.7.7~Fig.7.8)

( nucleus ) ( vacuole )

( nucleolus ) ( lysosome )

( chloroplast ) ( plasma membrane )

( mitochondrion ) ( microbody )

( endoplasmic reticulum ) ( peroxisome )

(Golgi body ; Golgi apparatus) ( glyoxysome )

( ribosome ) (cytoskeleton )


The nucleus contains a eukaryotic cell s genetic library fig 7 9

(The nucleus contains a eukaryotic cells genetic library)(Fig.7.9)

()( nuclear envelope )

()( nuclear plasma )( chromatin )

()( nucleolusnucleoli )EMrRNA


Ribosomes

( ribosomes)

()

()rRNA(Fig.7.10)

()( bound ribosomes )( polyribosomes )


Endomenbrane system

( endomenbrane system )

()( endomenbrane system )

a.( nuclear envelope )

b.( endoplasmic reticulum )

c.( Golgi apparatus )

d.( lysosomes )

e.( various kinds of vacuoles )

f.( peroxisomes )

g.( plasma membrane )


Endoplasmic reticulum

() ( endoplasmic reticulum )

1. endoplasmicreticulum (little net) ( membranous tubles ) ( cisternae ) (Fig.7.11)


Endoplasmic reticulum1

() ( endoplasmic reticulum )

2.

a. (rough endoplasmic reticulum, RER )

b. ( smooth endoplasmic reticulum, SER )


Endoplasmic reticulum2

() ( endoplasmic reticulum )

3.

a. (pancreas) (insulin) (glycoproteins)


Endoplasmic reticulum3

() ( endoplasmic reticulum )

3.

b. (transport vesicle)

c. ( phospholipids )

d.


Endoplasmic reticulum4

() ( endoplasmic reticulum )

4.

a.

b. ( glycogenolysis )

c. ( detoxification )

d.


Golgi apparatus golgi complex golgi body dictyosome golgi apparatus fig 7 12

()( Golgi apparatus, Golgi complex, Golgi body , Dictyosome, Golgi apparatus ) (Fig.7.12)

1. (modification) (sort)


A tour of the cell

()

2. :

a.

b.

c.


Lysosomes fig 7 13

() ( lysosomes )(Fig.7.13)

1.( hydrolytic enzymes )macromolecules


Lysosomes fig 7 131

() ( lysosomes )(Fig.7.13)

2.

a.

(1). (phagocytosis )

(2). autophage(Fig.7.137.14)

b.extracellular action


Lysosomes fig 7 132

() ( lysosomes )(Fig.7.13)

3.

  • (Storage disease)

  • 20


Vacuole

()vacuole

  • (Fig.7.15)


Vacuole1

()vacuole

1.food vacuoles

2.contractile vacuoles

3.

  • ,tonoplastanthocyanins


Peroxisomes

()peroxisomes

1. peroxidasecatalaseamino oxidase

H2O2+H2O 2H2O+O2

H2A+H2O 2H2O+A

catalase

peroxidase


Peroxisomes1

()peroxisomes

2.glyoxysomes(Fig.7.19)


Energy tranduction mitochondrion chloroplast

energy tranductionmitochondrionchloroplast

()mitochondrionmitochondria(Fig.7.17)

1.0.2-0.5 ATPDNA70S


Mitochondrium mitochondria

()mitochondriummitochondria

2.symbiosisthe symbiotic hypothesis of mitochondria

3.


Chloroplast fig 7 18

()( chloroplast )(Fig.7.18)

1. ( granum ) ( photosynthesis ) ( light reaction )2-10 ( compartment ) ( thylakoid ) ( stroma ) DNA70S


Chloroplast fig 7 181

()( chloroplast )(Fig.7.18)

2. ( symbiosis )


Cytoskeleton

( cytoskeleton )

() ( microtubules )( microfilaments ) ( intermediate filaments ) (Fig.7.20)

1. 25nmtubulin


Cytoskeleton1

( cytoskeleton )

2.( actin-like )

3.8-12nm( keratins )


A tour of the cell

( cytoskeleton )

()motor molecules(Fig. 7.21Table 7.2)


Centrosome

centrosome

  • centriosomecentrioles (Fig 7.22)


A tour of the cell

( flagellumflagella) ( cilliumcillia )(Fig. 7.23,7.24,7.25)


Cell wall

( Cell Wall )

() ( middle lamella ) ( primary cell wall )


Cell wall1

( Cell Wall )

() ( secondary cell wall ) ( lignin ) ( lignification ) ( suberin ) ( cutin )Fig. 7.28


Extracellular matrix ecm

( extracellular matrix ECM )

() ( support ) ( adhesion ) ( movement ) ( development )


Extracellular matrix ecm1

( extracellular matrix ECM )

() ( glycoproteins ) ( collagen ) ( fiber ) (collagen fibers)(protesglycan)(Fig. 7. 29)


Extracellular matrix ecm2

( extracellular matrix ECM )

() ECM(fibronectin) (receptor protein)-integrins(communication)


Junction

( junction )

() (physical contact) ( adhere ) ( interact ) ( communicate ) ( junction ) (Fig. 7.30)


Junction1

( junction )

()

  • oligosaccharides


Junction2

( junction )

()

1.

a. gap junction

b. mucopolysaccharide

c.

d.( leakage )


Junction3

( junction )

()

2.

a.

b.


A tour of the cell

(parts)

(The cell is a living unit greater than the sum of its parts)


A tour of the cell

1.Compbell, NA and Reece,JB (2002)

Biology(6th.ed).Chap.7.A tour of the cell.p.108-137.

2.Becker, Kleismith and Hardin. (2003). The World of

the Cell. (5th edition). ISSN-O-80532-4547-7.

3.Alberts B., Johnson A., Lewis J., Raff M., Roberts K.

and Walter P.. (2002). Molecular Biology of the Cell.

(4th edition). Garland Science Co. New York. USA.


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