Dual Use Research of Concern. Boston University and Boston Medical Center . Scope of Presentation. The goal of this presentation is to provide a general awareness on the dual use dilemma as it relates to academic research. The specific aims are to provide:
Boston University and Boston Medical Center
The National Science Advisory Board for Biosecurity (NSABB)
has been charged to develop guidelines for the oversight of
“Dual Use Research of Concern” (DURC)
Definition of DURC*
“Research that, based on current understanding, can be reasonably anticipated to provide knowledge, products, or technologies that could be directly misapplied by others to pose a threat to public health and safety, agricultural crops and other plants, animals, the environment, or materiel”.
*Source: National Science Advisory Board for Biosecurity (NSABB)
Re-construction of 1918 flu virus published papers (Tumpey 2005 and Taubenberger 2005).
Information may be misused by others to construct similar deadly pathogens for bio-weapon.
Other Example: Aerosolized drug delivery
Engineered large porous micro carriers (“whiffle balls”) deliver more drugs into the lung.
Information may allow others to use the technology/approach for delivery aerosolized bio-weapons.
The Federal Government is expected to establish guidelines, based on NSABB recommendations, that will require research institutions to govern the execution and public communication of DURC.
* Strongly promote the free and open exchange of information.
In July 2009, BU-BMC Advisory Committee on DURC issued its report
with the following key recommendations to be implemented in two
NSABB identified seven categories that meets DURC:
* Already part of screening process of research by the IBC.
Initial assessment of research by Principal Investigator for Dual Use
Technical Safety Committee Review
IBC / LSC
Federal Advisory Panel or Private Sector Consultant
OGC, Administration, Others
The Institution will need to work with you to seek advise and recommendations in order to implement the recommendations by the Ad-hoc committee on DURC.