Enzymes 2 nd year dentistry
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Enzymes 2 nd Year Dentistry. By Eman Mokbel Alissa, Ph.D. Lecture (1): Lecture Content. Enzyme Definition Enzymes vs. biological catalysts Enzyme Nomenclature Recommended name and IUBMB system Enzyme Classification Simple and complex enzymes. Lecture (2): Lecture Content. Coenzymes

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Enzymes 2 nd Year Dentistry

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Enzymes 2 nd year dentistry

Enzymes 2nd Year Dentistry

By

Eman Mokbel Alissa, Ph.D.


Lecture 1 lecture content

Lecture (1): Lecture Content

  • Enzyme Definition

  • Enzymes vs. biological catalysts

  • Enzyme Nomenclature

    • Recommended name and IUBMB system

  • Enzyme Classification

    • Simple and complex enzymes


Lecture 2 lecture content

Lecture (2): Lecture Content

  • Coenzymes

  • Properties of enzymes:

    • Catalytic efficiency

    • Location within cell

    • Enzyme active site

    • Specificity

  • 2 hypothesis of enzyme specificity


Lecture 3 lecture content

Lecture (3): Lecture Content

  • Mechanism of enzyme action

  • Mechanism of enzyme catalysis

  • The Enzyme Substrate Complex

  • Factors Affecting Reaction Velocity


Lecture 4 lecture content

Lecture (4): Lecture Content

  • Enzymes Kinetics

  • Michaelis-Menten equation

  • Linweaver-plot

  • Types of Enzyme Specificity

  • Mechanisms of enzyme catalysis


Lecture 5 lecture content

Lecture (5): Lecture Content

  • Enzymes Inhibitors:

    • Reversible and irreversible

    • Competitive and uncompetitive

  • Medical relevance of enzyme Inhibitors

  • Antibiotics

  • Enzymes Clinical Application


Lecture 6 lecture content

Lecture (6): Lecture Content

  • Common Terminology

  • Allosteric enzymes

  • Allosterism vs. cooperativity

  • Allosteric Enzymes Kinetics

  • Feed back inhibition

  • Homotropic and Heterotropic effectors

  • Enzyme Activity Regulation

    • Induction and repression

    • Covalent modification

    • Compartmentalization


Lecture 7 lecture content

Lecture (7): Lecture Content

  • Enzyme measurements

  • Plasma Enzymes

  • Serum enzymes in Diagnosis

  • Isoenzymes


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