OPIOIDS . Dr. Hisham Zein Alabdin. Plant origin. It is the dried extract of the poppy plant: Popover somniferum . Raw opium typically is composed of at least 10% morphine. Opioids. The term opioids are compounds that exert pharmacologic activity at opioids receptors.
Dr. Hisham Zein Alabdin
The term opioids are compounds that exert pharmacologic activity at opioids receptors.
Are combination of stimulation and depression. There is transient euphoria followed by dysphoria .
Mainly constipation due to:
1- Decreased gastrointestinal motility.
2- Decreased HCL secretion
3- Increased antral muscle tone and duodenal muscle tone.
4- Increased iliocecal valve and sphincter tone.
Aggravates biliary colic by:
1- Constriction of sphincter of Oddi.
2- Increased biliary tract pressure.
3-Decreased biliary secretion.
Flushing, urticaria, and skin rash.
It gives a positive result about 30 minutes after a single dose and remains +ve up to 36 hrs and up to 72 hrs after repeated doses.