OPIOIDS . Dr. Hisham Zein Alabdin. Plant origin. It is the dried extract of the poppy plant: Popover somniferum . Raw opium typically is composed of at least 10% morphine. Opioids. The term opioids are compounds that exert pharmacologic activity at opioids receptors.
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Dr. Hisham Zein Alabdin
The term opioids are compounds that exert pharmacologic activity at opioids receptors.
Are combination of stimulation and depression. There is transient euphoria followed by dysphoria .
Mainly constipation due to:
1- Decreased gastrointestinal motility.
2- Decreased HCL secretion
3- Increased antral muscle tone and duodenal muscle tone.
4- Increased iliocecal valve and sphincter tone.
Aggravates biliary colic by:
1- Constriction of sphincter of Oddi.
2- Increased biliary tract pressure.
3-Decreased biliary secretion.
Flushing, urticaria, and skin rash.
It gives a positive result about 30 minutes after a single dose and remains +ve up to 36 hrs and up to 72 hrs after repeated doses.