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CASE 2

CASE 2. 5 8 yo man IVDU in past….last used 35 yrs ago Genotype 1a Chronic Hepatitis C Type II Diabetes Private drug plan coverage. CASE 2. Hepatitis C history 2005 Liver Biopsy… gd 2 activity and gd 3-4 fibrosis Treated with Peg Inf /RBV 1000mg/day (70kg) Seemingly adherent.

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CASE 2

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  1. CASE 2 • 58 yo man • IVDU in past….last used 35 yrs ago • Genotype 1a Chronic Hepatitis C • Type II Diabetes • Private drug plan coverage

  2. CASE 2 Hepatitis C history 2005 Liver Biopsy…gd 2 activity and gd 3-4 fibrosis Treated with Peg Inf/RBV 1000mg/day (70kg) Seemingly adherent

  3. CASE 2 Hepatitis C history 2005/6 Week 0 HCVRNA..1.16x10E6 Week 4 HCVRNA…3.65 x 10E4 Week 12 HCVRNA…1.08x 10E2 Week 24 HCVRNA…undetectable Week 48 HCVRNA…undetectable 3 monthspost therapy F/U…5.90 x 10E5

  4. CASE 2 • Would you retreat… • What would be the projected chance of cure • Is he a candidate for response guided therapy… • How long would you treat with each agent

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